| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 100 | 23 | 23 | 11 | 4 | 3.21 | .250 | 0.99 | 6.3 | 2.6 | 9.1 | 157.0 | 110 | 59 | 56 | 19 | 45 | 159 | 2 | 0 | 0 | 1 | 16 | 2 | 1 | 3.45 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 89 | 24 | 23 | 10 | 8 | 3.33 | .297 | 1.26 | 7.9 | 3.4 | 6.4 | 162.1 | 142 | 63 | 60 | 13 | 62 | 115 | 6 | 0 | 0 | 2 | 17 | 2 | 3 | 3.81 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 84 | 22 | 22 | 9 | 7 | 4.45 | .281 | 1.15 | 7.5 | 2.9 | 8.4 | 127.1 | 106 | 66 | 63 | 14 | 41 | 118 | 1 | 0 | 0 | 0 | 11 | 2 | 1 | 3.59 |
| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 78 | 22 | 22 | 9 | 4 | 3.71 | .286 | 1.19 | 8.7 | 2.1 | 7.8 | 140.2 | 135 | 58 | 58 | 20 | 33 | 121 | 2 | 0 | 0 | 1 | 13 | 1 | 3 | 3.86 |
| RP | Doolittle, S.Doolittle, Sean † # >> | 31 | 2018 | L | 99 | 60 | 0 | 7 | 7 | 5.91 | .307 | 1.25 | 8.7 | 2.5 | 9.3 | 64.0 | 62 | 42 | 42 | 14 | 18 | 66 | 0 | 18 | 6 | 0 | 0 | 5 | 1 | 4.86 |
| RP | Petit, Y.Petit, Yusmeiro >> | 35 | 2019 | R | 71 | 30 | 0 | 1 | 0 | 3.03 | .288 | 1.22 | 8.3 | 2.8 | 9.2 | 38.2 | 35 | 13 | 13 | 5 | 12 | 39 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.61 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 89 | 49 | 0 | 3 | 1 | 3.20 | .303 | 1.27 | 5.8 | 5.6 | 10.5 | 59.0 | 38 | 21 | 21 | 3 | 37 | 69 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 3.31 |
| RP | Soriano, R.Soriano, Rafael >> | 31 | 2010 | R | 80 | 46 | 0 | 2 | 4 | 4.04 | .307 | 1.31 | 8.1 | 3.7 | 7.5 | 49.0 | 44 | 24 | 22 | 8 | 20 | 41 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 81 | 35 | 0 | 3 | 2 | 4.25 | .357 | 1.56 | 9.3 | 4.8 | 8.5 | 36.0 | 37 | 17 | 17 | 4 | 19 | 34 | 0 | 1 | 2 | 0 | 0 | 4 | 2 | 4.47 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 21 | 0 | 3 | 0 | 3.12 | .304 | 1.23 | 7.6 | 3.5 | 9.3 | 26.0 | 22 | 9 | 9 | 4 | 10 | 27 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 4.31 |
| RP | McHugh, C.McHugh, Collin >> | 31 | 2018 | R | 64 | 20 | 0 | 1 | 1 | 3.22 | .272 | 1.12 | 6.5 | 3.7 | 12.7 | 22.1 | 16 | 8 | 8 | 1 | 9 | 31 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2.00 |