| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 21 | 21 | 11 | 7 | 2.62 | .261 | 1.02 | 7.1 | 2.1 | 5.9 | 144.1 | 114 | 43 | 42 | 11 | 33 | 95 | 6 | 0 | 0 | 4 | 15 | 6 | 5 | 3.49 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 20 | 20 | 14 | 3 | 2.59 | .255 | 1.00 | 5.7 | 3.3 | 7.4 | 135.2 | 85 | 40 | 39 | 11 | 50 | 111 | 2 | 0 | 0 | 2 | 16 | 4 | 1 | 3.61 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 29 | 21 | 20 | 8 | 9 | 5.07 | .345 | 1.58 | 11.0 | 3.2 | 7.3 | 103.0 | 126 | 62 | 58 | 12 | 37 | 83 | 0 | 0 | 0 | 0 | 10 | 0 | 4 | 3.98 |
| SP | Spahn, W.Spahn, Warren >> | 32 | 1953 | L | 20 | 19 | 19 | 9 | 7 | 3.34 | .283 | 1.19 | 8.3 | 2.4 | 4.7 | 121.1 | 112 | 45 | 45 | 7 | 32 | 63 | 4 | 0 | 0 | 1 | 12 | 0 | 0 | 3.50 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 45 | 0 | 3 | 6 | 3.18 | .286 | 1.20 | 6.9 | 4.0 | 10.1 | 56.2 | 43 | 21 | 20 | 1 | 25 | 63 | 0 | 24 | 2 | 0 | 0 | 0 | 0 | 2.32 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 47 | 0 | 0 | 1 | 2.78 | .292 | 1.24 | 7.0 | 4.2 | 6.2 | 64.2 | 50 | 21 | 20 | 6 | 30 | 44 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.25 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 36 | 0 | 2 | 0 | 3.20 | .240 | 0.93 | 6.8 | 1.6 | 7.4 | 50.2 | 38 | 18 | 18 | 3 | 9 | 41 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 2.74 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 30 | 1983 | R | 29 | 27 | 0 | 1 | 1 | 3.96 | .309 | 1.32 | 9.5 | 2.3 | 3.6 | 50.0 | 53 | 28 | 22 | 4 | 13 | 20 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.08 |