| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 4 | 4 | 1 | 1 | 3.51 | .306 | 1.29 | 8.6 | 3.2 | 6.8 | 25.2 | 24 | 11 | 10 | 2 | 9 | 19 | 1 | 0 | 0 | 1 | 2 | 1 | 2 | 3.72 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 77 | 4 | 4 | 0 | 1 | 2.33 | .289 | 1.22 | 5.7 | 5.3 | 7.7 | 27.0 | 17 | 7 | 7 | 3 | 16 | 23 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.52 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 4 | 4 | 1 | 2 | 5.56 | .333 | 1.46 | 10.6 | 2.9 | 9.0 | 22.2 | 26 | 14 | 14 | 3 | 7 | 22 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 3.86 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 10 | 0 | 1 | 0 | 3.97 | .292 | 1.15 | 9.0 | 1.6 | 9.0 | 11.1 | 11 | 6 | 5 | 2 | 2 | 11 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.18 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 14 | 0 | 1 | 1 | 1.80 | .237 | 0.87 | 4.8 | 3.0 | 7.2 | 15.0 | 8 | 3 | 3 | 1 | 5 | 12 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.47 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 11 | 0 | 1 | 0 | 3.09 | .222 | 0.77 | 5.7 | 1.6 | 5.7 | 11.2 | 7 | 4 | 4 | 0 | 2 | 7 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.55 |