| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 21 | 21 | 9 | 7 | 3.07 | .275 | 1.10 | 7.5 | 2.4 | 8.4 | 152.1 | 126 | 52 | 52 | 16 | 41 | 142 | 5 | 0 | 0 | 2 | 15 | 6 | 2 | 3.43 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 20 | 20 | 9 | 8 | 3.62 | .302 | 1.28 | 8.6 | 3.0 | 6.1 | 129.1 | 123 | 56 | 52 | 12 | 43 | 88 | 1 | 0 | 0 | 1 | 13 | 2 | 2 | 3.89 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 20 | 20 | 9 | 7 | 4.35 | .300 | 1.27 | 8.6 | 2.9 | 7.8 | 140.2 | 133 | 75 | 68 | 21 | 45 | 121 | 1 | 0 | 0 | 1 | 8 | 3 | 2 | 4.25 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 20 | 20 | 4 | 8 | 5.55 | .341 | 1.55 | 10.8 | 3.2 | 4.5 | 97.1 | 116 | 66 | 60 | 17 | 35 | 49 | 0 | 0 | 0 | 0 | 6 | 0 | 3 | 5.35 |
| SU | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 35 | 0 | 1 | 0 | 4.03 | .283 | 1.16 | 5.9 | 4.5 | 9.2 | 38.0 | 25 | 18 | 17 | 3 | 19 | 39 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 3.55 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 86 | 37 | 0 | 4 | 4 | 2.92 | .275 | 1.14 | 7.1 | 3.2 | 10.2 | 37.0 | 29 | 13 | 12 | 0 | 13 | 42 | 0 | 19 | 1 | 0 | 0 | 0 | 2 | 1.78 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 43 | 0 | 3 | 0 | 3.56 | .348 | 1.58 | 9.0 | 5.2 | 10.0 | 43.0 | 43 | 18 | 17 | 4 | 25 | 48 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 3.79 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 35 | 0 | 2 | 1 | 2.35 | .246 | 0.96 | 6.1 | 2.5 | 10.2 | 46.0 | 31 | 13 | 12 | 6 | 13 | 52 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 3.35 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 32 | 0 | 3 | 2 | 4.61 | .272 | 1.12 | 8.1 | 2.0 | 8.8 | 41.0 | 37 | 24 | 21 | 6 | 9 | 40 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.61 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 27 | 0 | 1 | 1 | 3.81 | .303 | 1.31 | 8.4 | 3.5 | 11.6 | 28.1 | 26 | 13 | 12 | 2 | 11 | 36 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.54 |