| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 7 | 7 | 1 | 3 | 3.89 | .298 | 1.27 | 8.8 | 2.7 | 9.8 | 44.0 | 43 | 22 | 19 | 3 | 13 | 48 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 2.59 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 7 | 7 | 2 | 1 | 5.63 | .337 | 1.53 | 9.5 | 4.3 | 8.3 | 40.0 | 42 | 28 | 25 | 5 | 19 | 37 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 4.20 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 6 | 6 | 1 | 3 | 9.35 | .418 | 2.12 | 14.2 | 4.8 | 5.5 | 26.0 | 41 | 28 | 27 | 4 | 14 | 16 | 0 | 0 | 0 | 0 | 1 | 1 | 3 | 5.50 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 18 | 0 | 2 | 0 | 1.83 | .224 | 0.81 | 5.2 | 2.4 | 9.9 | 19.2 | 11 | 4 | 4 | 1 | 5 | 21 | 0 | 9 | 1 | 0 | 0 | 1 | 1 | 2.42 |
| SU | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 20 | 0 | 3 | 1 | 3.24 | .286 | 1.16 | 7.2 | 3.2 | 5.0 | 25.0 | 20 | 9 | 9 | 1 | 9 | 14 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.60 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 22 | 0 | 4 | 0 | 3.92 | .303 | 1.21 | 6.3 | 5.0 | 6.8 | 20.2 | 14 | 9 | 9 | 1 | 11 | 15 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.10 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 5 | 1 | 0 | 1 | 12.27 | .463 | 2.59 | 16.7 | 7.7 | 5.1 | 7.1 | 13 | 10 | 10 | 2 | 6 | 4 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 8.14 |