| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 36 | 36 | 17 | 14 | 3.90 | .298 | 1.25 | 8.1 | 3.1 | 8.0 | 249.0 | 225 | 112 | 108 | 26 | 87 | 220 | 4 | 0 | 0 | 1 | 21 | 5 | 7 | 3.70 |
| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 92 | 35 | 35 | 9 | 22 | 6.03 | .345 | 1.56 | 11.0 | 3.0 | 5.3 | 207.1 | 253 | 142 | 139 | 27 | 70 | 122 | 4 | 0 | 0 | 1 | 13 | 5 | 3 | 4.60 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 34 | 34 | 10 | 14 | 4.59 | .307 | 1.31 | 9.1 | 2.7 | 3.4 | 223.1 | 225 | 120 | 114 | 24 | 68 | 84 | 5 | 0 | 0 | 0 | 15 | 4 | 8 | 4.61 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 33 | 33 | 12 | 11 | 4.91 | .325 | 1.44 | 9.6 | 3.4 | 5.4 | 209.0 | 222 | 122 | 114 | 21 | 80 | 126 | 5 | 0 | 0 | 0 | 18 | 0 | 5 | 4.25 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 32 | 31 | 14 | 13 | 5.11 | .332 | 1.47 | 9.6 | 3.7 | 7.9 | 199.0 | 212 | 116 | 113 | 20 | 81 | 175 | 4 | 0 | 0 | 1 | 13 | 4 | 4 | 3.83 |
| SU | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 64 | 0 | 2 | 2 | 3.62 | .313 | 1.35 | 7.7 | 4.6 | 10.6 | 69.2 | 59 | 30 | 28 | 6 | 35 | 81 | 0 | 4 | 5 | 0 | 0 | 1 | 2 | 3.35 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 68 | 0 | 6 | 2 | 2.43 | .317 | 1.36 | 9.5 | 2.8 | 7.8 | 74.0 | 78 | 21 | 20 | 4 | 23 | 64 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 2.99 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 40 | 0 | 3 | 1 | 1.97 | .251 | 1.01 | 5.4 | 3.8 | 7.0 | 45.2 | 27 | 11 | 10 | 3 | 19 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.58 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 87 | 54 | 0 | 6 | 5 | 2.48 | .262 | 1.05 | 7.0 | 2.5 | 9.3 | 54.1 | 42 | 17 | 15 | 2 | 15 | 56 | 0 | 32 | 4 | 0 | 0 | 1 | 1 | 2.30 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 25 | 0 | 1 | 0 | 6.93 | .378 | 1.78 | 13.1 | 3.4 | 7.9 | 24.2 | 35 | 20 | 19 | 6 | 9 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.75 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 12 | 0 | 1 | 0 | 1.15 | .277 | 1.15 | 7.8 | 3.0 | 9.6 | 15.2 | 13 | 2 | 2 | 1 | 5 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.73 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 18 | 0 | 0 | 0 | 3.80 | .290 | 1.23 | 7.4 | 3.9 | 6.3 | 23.2 | 19 | 12 | 10 | 2 | 10 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.04 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 79 | 0 | 3 | 0 | 3.49 | .280 | 1.14 | 6.6 | 3.7 | 6.6 | 85.0 | 62 | 36 | 33 | 6 | 35 | 62 | 0 | 2 | 0 | 0 | 0 | 2 | 11 | 3.76 |