| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 96 | 35 | 35 | 17 | 10 | 2.92 | .262 | 1.05 | 6.5 | 2.9 | 8.0 | 258.2 | 187 | 87 | 84 | 19 | 84 | 228 | 14 | 0 | 0 | 3 | 25 | 4 | 2 | 3.21 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 91 | 34 | 34 | 15 | 12 | 3.88 | .277 | 1.12 | 7.9 | 2.2 | 9.3 | 231.2 | 203 | 101 | 100 | 22 | 57 | 239 | 10 | 0 | 0 | 1 | 21 | 6 | 7 | 2.99 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 64 | 33 | 33 | 16 | 11 | 4.11 | .309 | 1.33 | 7.9 | 4.1 | 7.8 | 210.1 | 185 | 100 | 96 | 23 | 95 | 181 | 6 | 0 | 0 | 1 | 17 | 2 | 3 | 4.09 |
| SP | Plesac, Z.Plesac, Zach >> | 25 | 2020 | R | 94 | 31 | 31 | 0 | 7 | 4.59 | .285 | 1.20 | 8.8 | 2.0 | 7.5 | 80.1 | 78 | 43 | 41 | 9 | 18 | 67 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.46 |
| RP | Perez, O.Perez, Oliver >> | 37 | 2018 | L | 98 | 81 | 0 | 1 | 6 | 3.55 | .268 | 1.06 | 7.3 | 2.3 | 9.2 | 96.1 | 78 | 38 | 38 | 6 | 24 | 98 | 0 | 12 | 3 | 0 | 0 | 4 | 3 | 2.65 |
| RP | Clase, E.Clase, Emmanuel >> | 24 | 2022 | R | 88 | 66 | 0 | 5 | 2 | 2.41 | .249 | 0.98 | 7.4 | 1.5 | 8.8 | 89.2 | 73 | 26 | 24 | 4 | 15 | 87 | 0 | 5 | 4 | 0 | 0 | 1 | 4 | 2.17 |
| RP | Manship, J.Manship, Jeff >> | 30 | 2015 | R | 92 | 55 | 0 | 3 | 3 | 3.34 | .276 | 1.14 | 8.1 | 2.2 | 4.8 | 70.0 | 63 | 27 | 26 | 8 | 17 | 37 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 4.16 |
| RP | Clippard, T.Clippard, Tyler # >> | 34 | 2019 | R | 74 | 33 | 0 | 2 | 3 | 5.60 | .333 | 1.47 | 9.8 | 3.6 | 7.5 | 35.1 | 38 | 24 | 22 | 7 | 14 | 29 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.23 |
| RP | McKenzie, T.McKenzie, Triston >> | 22 | 2020 | R | 68 | 51 | 0 | 16 | 1 | 4.69 | .336 | 1.49 | 9.6 | 3.8 | 8.5 | 119.0 | 127 | 69 | 62 | 14 | 50 | 112 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 4.01 |
| RP | Sandlin, N.Sandlin, Nick >> | 26 | 2023 | R | 43 | 21 | 0 | 0 | 1 | 5.31 | .315 | 1.33 | 8.6 | 3.6 | 11.7 | 20.1 | 19 | 13 | 12 | 5 | 8 | 26 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.00 |