| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 70 | 20 | 20 | 5 | 7 | 3.38 | .283 | 1.18 | 8.0 | 2.6 | 8.6 | 120.0 | 106 | 49 | 45 | 10 | 35 | 115 | 0 | 0 | 0 | 0 | 14 | 1 | 2 | 3.07 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 77 | 19 | 19 | 5 | 9 | 5.09 | .324 | 1.41 | 9.1 | 3.6 | 7.4 | 111.1 | 112 | 67 | 63 | 16 | 45 | 91 | 1 | 0 | 0 | 0 | 10 | 3 | 2 | 4.53 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 72 | 18 | 18 | 8 | 5 | 2.31 | .264 | 1.07 | 6.0 | 3.6 | 7.2 | 121.0 | 81 | 32 | 31 | 5 | 48 | 97 | 0 | 0 | 0 | 0 | 15 | 1 | 4 | 3.15 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 58 | 18 | 18 | 12 | 3 | 3.14 | .273 | 1.13 | 7.6 | 2.6 | 7.6 | 100.1 | 84 | 38 | 35 | 15 | 29 | 84 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 4.14 |
| RP | Lamet, D.Lamet, Dinelson † >> | 27 | 2020 | R | 72 | 51 | 0 | 8 | 5 | 2.50 | .293 | 1.20 | 6.6 | 4.2 | 9.8 | 104.1 | 76 | 30 | 29 | 8 | 49 | 113 | 0 | 7 | 3 | 0 | 0 | 5 | 0 | 3.38 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 97 | 39 | 0 | 2 | 1 | 1.85 | .236 | 0.90 | 5.1 | 3.2 | 9.2 | 48.2 | 27 | 10 | 10 | 4 | 17 | 49 | 0 | 6 | 1 | 0 | 0 | 1 | 1 | 3.17 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 88 | 29 | 0 | 1 | 1 | 3.51 | .306 | 1.25 | 7.2 | 4.3 | 7.6 | 25.2 | 20 | 10 | 10 | 3 | 12 | 21 | 0 | 8 | 1 | 0 | 0 | 2 | 1 | 4.56 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 62 | 14 | 0 | 3 | 1 | 3.07 | .302 | 1.30 | 7.7 | 4.5 | 5.8 | 14.2 | 12 | 5 | 5 | 1 | 7 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.14 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 8 | 0 | 0 | 1 | 8.00 | .400 | 2.00 | 13.0 | 5.0 | 8.0 | 9.0 | 13 | 8 | 8 | 1 | 5 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 59 | 19 | 0 | 0 | 0 | 5.50 | .349 | 1.61 | 9.0 | 5.5 | 10.0 | 18.0 | 18 | 11 | 11 | 3 | 11 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.78 |