| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 32 | 32 | 15 | 11 | 2.92 | .270 | 1.09 | 7.6 | 2.2 | 9.0 | 234.0 | 198 | 82 | 76 | 22 | 57 | 234 | 5 | 0 | 0 | 1 | 23 | 4 | 2 | 3.00 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 96 | 32 | 32 | 8 | 11 | 4.66 | .335 | 1.50 | 8.9 | 4.6 | 5.7 | 179.2 | 178 | 99 | 93 | 20 | 91 | 114 | 1 | 0 | 0 | 0 | 15 | 2 | 3 | 4.74 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 79 | 30 | 30 | 7 | 13 | 5.61 | .343 | 1.55 | 10.3 | 3.7 | 6.2 | 171.2 | 196 | 114 | 107 | 22 | 70 | 118 | 4 | 0 | 0 | 0 | 11 | 3 | 11 | 4.57 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 99 | 69 | 0 | 3 | 4 | 4.01 | .297 | 1.27 | 7.5 | 3.9 | 8.9 | 74.0 | 62 | 37 | 33 | 9 | 32 | 73 | 0 | 35 | 5 | 0 | 0 | 0 | 3 | 3.91 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 97 | 85 | 0 | 4 | 5 | 5.33 | .334 | 1.44 | 8.8 | 4.1 | 9.9 | 103.0 | 101 | 65 | 61 | 13 | 47 | 113 | 0 | 1 | 4 | 0 | 0 | 7 | 6 | 4.02 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 74 | 0 | 2 | 6 | 4.45 | .338 | 1.49 | 8.6 | 4.9 | 9.9 | 83.0 | 79 | 47 | 41 | 7 | 45 | 91 | 0 | 1 | 6 | 0 | 0 | 3 | 5 | 3.64 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 27 | 2007 | R | 92 | 62 | 0 | 6 | 5 | 5.80 | .361 | 1.70 | 10.5 | 4.9 | 12.3 | 68.1 | 79 | 50 | 44 | 12 | 37 | 93 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 4.19 |
| RP | Brasier, R.Brasier, Ryan >> | 30 | 2018 | R | 73 | 47 | 0 | 3 | 1 | 2.40 | .284 | 1.17 | 6.9 | 3.7 | 6.8 | 56.1 | 43 | 15 | 15 | 1 | 23 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.02 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 68 | 40 | 0 | 2 | 2 | 3.88 | .286 | 1.20 | 8.5 | 2.4 | 9.8 | 53.1 | 50 | 24 | 23 | 10 | 14 | 58 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.06 |