| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 34 | 34 | 11 | 16 | 4.40 | .303 | 1.30 | 8.6 | 3.1 | 8.7 | 233.0 | 222 | 117 | 114 | 36 | 80 | 226 | 3 | 0 | 0 | 1 | 17 | 2 | 2 | 4.12 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 33 | 33 | 7 | 12 | 5.24 | .322 | 1.40 | 8.9 | 3.7 | 8.7 | 201.0 | 199 | 119 | 117 | 35 | 82 | 195 | 2 | 0 | 0 | 0 | 13 | 6 | 11 | 4.64 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 30 | 30 | 14 | 8 | 4.73 | .330 | 1.47 | 8.4 | 4.8 | 4.4 | 209.1 | 196 | 117 | 110 | 29 | 111 | 102 | 2 | 0 | 0 | 0 | 12 | 3 | 3 | 5.46 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 85 | 0 | 6 | 9 | 4.01 | .303 | 1.29 | 6.9 | 4.7 | 7.6 | 139.0 | 107 | 67 | 62 | 13 | 72 | 117 | 0 | 7 | 5 | 0 | 0 | 2 | 0 | 4.13 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 77 | 0 | 1 | 6 | 4.36 | .347 | 1.57 | 7.4 | 6.8 | 9.3 | 86.2 | 71 | 42 | 42 | 9 | 65 | 89 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 4.63 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 64 | 0 | 3 | 8 | 5.54 | .317 | 1.39 | 10.0 | 2.7 | 7.5 | 74.2 | 82 | 49 | 46 | 14 | 22 | 62 | 0 | 8 | 3 | 0 | 0 | 0 | 5 | 4.68 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 52 | 0 | 5 | 2 | 3.05 | .253 | 1.02 | 5.3 | 3.9 | 8.7 | 65.0 | 38 | 25 | 22 | 7 | 28 | 63 | 0 | 5 | 3 | 0 | 0 | 0 | 1 | 3.75 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 54 | 4 | 1 | 1 | 1 | 8.38 | .383 | 1.76 | 13.0 | 4.0 | 4.0 | 9.2 | 13 | 9 | 9 | 3 | 4 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 8.11 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 27 | 0 | 1 | 5 | 3.83 | .295 | 1.24 | 8.1 | 3.2 | 7.1 | 51.2 | 46 | 23 | 22 | 4 | 18 | 40 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 3.57 |