| SP | McNally, D.McNally, Dave # >> | 26 | 1968 | L | 96 | 34 | 34 | 13 | 16 | 4.14 | .299 | 1.25 | 8.7 | 2.5 | 5.0 | 260.2 | 252 | 128 | 120 | 27 | 73 | 145 | 7 | 0 | 0 | 1 | 17 | 8 | 5 | 4.17 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 33 | 33 | 9 | 19 | 5.57 | .337 | 1.50 | 10.1 | 3.4 | 5.4 | 213.1 | 240 | 137 | 132 | 36 | 80 | 128 | 4 | 0 | 0 | 0 | 17 | 5 | 12 | 5.19 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 32 | 32 | 10 | 14 | 4.47 | .302 | 1.27 | 8.6 | 2.8 | 4.6 | 229.2 | 219 | 118 | 114 | 28 | 72 | 116 | 4 | 0 | 0 | 0 | 20 | 7 | 7 | 4.61 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 32 | 32 | 12 | 16 | 4.94 | .318 | 1.37 | 9.4 | 2.9 | 7.1 | 227.2 | 238 | 132 | 125 | 33 | 73 | 180 | 3 | 0 | 0 | 1 | 12 | 7 | 4 | 4.36 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 87 | 0 | 8 | 5 | 3.45 | .288 | 1.20 | 7.1 | 3.7 | 8.7 | 107.0 | 84 | 41 | 41 | 10 | 44 | 103 | 0 | 11 | 6 | 0 | 0 | 2 | 4 | 3.58 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 67 | 0 | 3 | 5 | 4.24 | .298 | 1.23 | 7.3 | 3.8 | 5.7 | 76.1 | 62 | 36 | 36 | 9 | 32 | 48 | 0 | 13 | 0 | 0 | 0 | 3 | 2 | 4.66 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 61 | 46 | 0 | 2 | 7 | 5.76 | .327 | 1.44 | 10.4 | 2.5 | 7.6 | 50.0 | 58 | 33 | 32 | 9 | 14 | 42 | 0 | 7 | 1 | 0 | 0 | 1 | 2 | 4.56 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 27 | 0 | 1 | 0 | 3.96 | .314 | 1.32 | 7.5 | 4.5 | 6.0 | 36.1 | 30 | 16 | 16 | 4 | 18 | 24 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 4.78 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 5 | 0 | 0 | 1 | 13.50 | .368 | 1.75 | 15.8 | 0.0 | 6.8 | 4.0 | 7 | 6 | 6 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |