| SP | Koufax, S.Koufax, Sandy $ >> | 30 | 1965 | L | 97 | 36 | 36 | 15 | 15 | 3.92 | .282 | 1.16 | 7.4 | 3.1 | 7.9 | 247.2 | 202 | 113 | 108 | 37 | 86 | 216 | 10 | 0 | 0 | 3 | 19 | 4 | 2 | 4.29 |
| SP | Joss, A.Joss, Addie $$ >> | 28 | 1908 | R | 83 | 33 | 33 | 15 | 14 | 4.06 | .284 | 1.18 | 8.5 | 2.1 | 4.0 | 217.1 | 206 | 101 | 98 | 20 | 51 | 96 | 6 | 0 | 0 | 3 | 18 | 2 | 3 | 4.05 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 33 | 33 | 8 | 12 | 3.88 | .306 | 1.31 | 8.5 | 3.3 | 9.0 | 209.0 | 197 | 91 | 90 | 24 | 76 | 210 | 1 | 0 | 0 | 1 | 21 | 3 | 7 | 3.62 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 73 | 32 | 30 | 11 | 11 | 4.09 | .311 | 1.32 | 7.6 | 4.2 | 8.5 | 185.0 | 157 | 85 | 84 | 20 | 87 | 175 | 1 | 0 | 0 | 1 | 20 | 6 | 12 | 4.02 |
| CL | Kimbrel, C.Kimbrel, Craig # >> | 24 | 2012 | R | 100 | 60 | 0 | 0 | 4 | 3.06 | .283 | 1.17 | 7.5 | 3.1 | 10.9 | 61.2 | 51 | 21 | 21 | 4 | 21 | 74 | 0 | 39 | 3 | 0 | 0 | 1 | 3 | 2.51 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 63 | 0 | 4 | 6 | 4.30 | .313 | 1.34 | 9.2 | 3.0 | 9.5 | 60.2 | 61 | 30 | 29 | 6 | 20 | 63 | 0 | 0 | 3 | 0 | 0 | 2 | 5 | 3.30 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 64 | 0 | 5 | 3 | 3.73 | .319 | 1.40 | 8.7 | 4.1 | 10.7 | 62.2 | 60 | 28 | 26 | 7 | 28 | 74 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.44 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 43 | 0 | 3 | 3 | 3.99 | .241 | 0.95 | 6.5 | 2.1 | 9.6 | 47.1 | 34 | 23 | 21 | 7 | 11 | 50 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.51 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 21 | 0 | 3 | 1 | 2.61 | .260 | 1.04 | 6.9 | 2.5 | 4.3 | 96.2 | 74 | 29 | 28 | 9 | 27 | 46 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.14 |