| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 27 | 27 | 11 | 8 | 2.64 | .275 | 1.11 | 7.4 | 2.6 | 7.4 | 174.0 | 143 | 52 | 51 | 11 | 51 | 143 | 0 | 0 | 0 | 0 | 20 | 4 | 3 | 3.13 |
| SP | Leonard, D.Leonard, Dutch † >> | 22 | 1914 | L | 91 | 26 | 26 | 12 | 7 | 3.77 | .293 | 1.23 | 7.4 | 3.7 | 4.3 | 167.0 | 137 | 72 | 70 | 11 | 69 | 79 | 3 | 0 | 0 | 1 | 17 | 2 | 3 | 4.19 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 25 | 25 | 12 | 7 | 2.98 | .263 | 1.05 | 7.5 | 2.0 | 6.1 | 169.1 | 140 | 60 | 56 | 15 | 37 | 114 | 3 | 0 | 0 | 1 | 18 | 4 | 2 | 3.53 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 24 | 24 | 11 | 9 | 4.13 | .291 | 1.22 | 8.6 | 2.4 | 7.4 | 174.1 | 166 | 80 | 80 | 27 | 46 | 144 | 4 | 0 | 0 | 1 | 11 | 3 | 3 | 4.21 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 31 | 0 | 1 | 2 | 4.26 | .312 | 1.29 | 7.5 | 4.4 | 7.5 | 31.2 | 26 | 15 | 15 | 1 | 15 | 26 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 3.39 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 23 | 0 | 2 | 2 | 2.42 | .316 | 1.34 | 6.1 | 6.1 | 7.8 | 22.1 | 15 | 6 | 6 | 2 | 15 | 19 | 0 | 5 | 1 | 0 | 0 | 1 | 3 | 4.64 |