| SP | Jimenez, U.Jimenez, Ubaldo # >> | 26 | 2010 | R | 48 | 25 | 25 | 10 | 10 | 5.05 | .322 | 1.41 | 9.5 | 3.1 | 7.9 | 169.1 | 179 | 100 | 95 | 13 | 59 | 149 | 2 | 0 | 0 | 2 | 11 | 3 | 13 | 3.34 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 39 | 24 | 24 | 11 | 10 | 4.48 | .318 | 1.39 | 7.3 | 5.3 | 7.0 | 124.2 | 100 | 65 | 62 | 16 | 73 | 96 | 0 | 0 | 0 | 0 | 5 | 1 | 4 | 4.92 |
| SP | Marquez, G.Marquez, German >> | 26 | 2021 | R | 33 | 24 | 23 | 7 | 4 | 5.78 | .356 | 1.64 | 10.4 | 4.4 | 6.1 | 123.0 | 142 | 86 | 79 | 16 | 60 | 84 | 0 | 0 | 0 | 0 | 9 | 2 | 4 | 4.84 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 68 | 76 | 0 | 4 | 3 | 3.59 | .311 | 1.34 | 8.6 | 3.6 | 8.8 | 82.2 | 78 | 37 | 33 | 9 | 33 | 80 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.72 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 66 | 69 | 0 | 10 | 3 | 3.70 | .324 | 1.41 | 7.8 | 4.9 | 8.8 | 73.0 | 63 | 30 | 30 | 9 | 40 | 71 | 0 | 4 | 6 | 0 | 0 | 2 | 3 | 4.38 |
| RP | Buchholz, T.Buchholz, Taylor >> | 27 | 2008 | R | 55 | 59 | 0 | 3 | 2 | 3.00 | .268 | 1.08 | 6.6 | 3.1 | 5.8 | 72.0 | 53 | 25 | 24 | 7 | 25 | 46 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 4.07 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 69 | 55 | 0 | 4 | 4 | 3.15 | .285 | 1.20 | 6.8 | 4.0 | 8.8 | 54.1 | 41 | 20 | 19 | 4 | 24 | 53 | 0 | 5 | 1 | 0 | 0 | 0 | 5 | 3.33 |