| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 50 | 28 | 28 | 8 | 11 | 4.56 | .304 | 1.29 | 7.7 | 3.9 | 7.1 | 179.2 | 154 | 97 | 91 | 18 | 77 | 142 | 3 | 0 | 0 | 2 | 14 | 4 | 6 | 4.08 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 40 | 28 | 28 | 14 | 9 | 4.83 | .332 | 1.49 | 9.4 | 4.0 | 8.1 | 164.0 | 172 | 89 | 88 | 21 | 72 | 148 | 1 | 0 | 0 | 1 | 10 | 1 | 3 | 4.20 |
| SP | Gomber, A.Gomber, Austin # >> | 27 | 2021 | L | 37 | 28 | 28 | 4 | 12 | 5.95 | .332 | 1.47 | 9.9 | 3.4 | 7.7 | 137.2 | 151 | 94 | 91 | 33 | 52 | 117 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 5.61 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 32 | 27 | 27 | 8 | 5 | 4.28 | .328 | 1.45 | 8.6 | 4.5 | 7.1 | 136.2 | 130 | 68 | 65 | 18 | 68 | 108 | 0 | 0 | 0 | 0 | 4 | 2 | 5 | 4.68 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 63 | 71 | 0 | 6 | 4 | 4.33 | .303 | 1.31 | 6.7 | 5.1 | 8.6 | 95.2 | 71 | 47 | 46 | 6 | 54 | 91 | 0 | 4 | 7 | 0 | 0 | 0 | 8 | 3.61 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 65 | 70 | 0 | 6 | 1 | 3.84 | .307 | 1.30 | 8.6 | 3.2 | 7.5 | 84.1 | 80 | 40 | 36 | 14 | 30 | 70 | 0 | 9 | 2 | 0 | 0 | 2 | 4 | 4.64 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 51 | 56 | 0 | 0 | 7 | 3.52 | .307 | 1.30 | 8.6 | 3.1 | 8.0 | 64.0 | 61 | 25 | 25 | 9 | 22 | 57 | 0 | 7 | 5 | 0 | 0 | 2 | 0 | 4.17 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 50 | 41 | 0 | 6 | 3 | 5.36 | .288 | 1.21 | 7.1 | 3.8 | 9.4 | 47.0 | 37 | 28 | 28 | 7 | 20 | 49 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.13 |
| RP | DeJean, M.DeJean, Mike >> | 35 | 2005 | R | 34 | 28 | 0 | 0 | 2 | 2.21 | .317 | 1.34 | 6.8 | 5.5 | 6.3 | 36.2 | 27 | 13 | 9 | 2 | 22 | 25 | 0 | 0 | 1 | 0 | 0 | 2 | 3 | 4.33 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 29 | 2010 | L | 30 | 24 | 1 | 6 | 6 | 4.51 | .304 | 1.29 | 7.1 | 4.6 | 5.6 | 103.2 | 81 | 54 | 52 | 18 | 53 | 64 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.63 |