| SP | deGrom, J.deGrom, Jacob † >> | 30 | 2018 | R | 92 | 29 | 29 | 14 | 12 | 2.75 | .263 | 1.06 | 7.2 | 2.4 | 8.5 | 232.1 | 185 | 78 | 71 | 21 | 61 | 219 | 15 | 0 | 0 | 3 | 21 | 3 | 4 | 3.12 |
| SP | Scherzer, M.Scherzer, Max >> | 38 | 2022 | R | 83 | 28 | 28 | 11 | 13 | 4.38 | .292 | 1.22 | 8.4 | 2.6 | 8.5 | 195.1 | 183 | 100 | 95 | 27 | 56 | 184 | 5 | 0 | 0 | 0 | 16 | 3 | 0 | 3.82 |
| SP | Martinez, P.Martinez, Pedro >> | 34 | 2005 | R | 75 | 27 | 27 | 10 | 10 | 3.95 | .303 | 1.29 | 8.3 | 3.4 | 6.2 | 205.0 | 188 | 93 | 90 | 18 | 77 | 142 | 8 | 0 | 0 | 0 | 13 | 2 | 3 | 3.91 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 76 | 27 | 27 | 9 | 9 | 4.48 | .322 | 1.40 | 9.5 | 3.1 | 8.6 | 190.2 | 201 | 101 | 95 | 24 | 66 | 181 | 6 | 0 | 0 | 1 | 12 | 5 | 3 | 3.86 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 61 | 27 | 26 | 14 | 11 | 3.55 | .300 | 1.26 | 7.8 | 3.7 | 8.3 | 197.2 | 170 | 80 | 78 | 20 | 80 | 182 | 7 | 0 | 0 | 1 | 15 | 4 | 5 | 3.75 |
| RP | Verrett, L.Verrett, Logan >> | 25 | 2015 | R | 70 | 46 | 0 | 1 | 5 | 4.68 | .299 | 1.24 | 6.8 | 4.3 | 8.1 | 50.0 | 38 | 26 | 26 | 5 | 24 | 45 | 0 | 5 | 0 | 0 | 0 | 2 | 0 | 4.06 |
| RP | Wagner, B.Wagner, Billy >> | 37 | 2008 | L | 63 | 63 | 0 | 2 | 4 | 3.92 | .307 | 1.31 | 9.2 | 2.6 | 8.1 | 41.1 | 42 | 21 | 18 | 6 | 12 | 37 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.05 |
| RP | Núnez, D.Núnez, Dedniel >> | 28 | 2024 | R | 62 | 21 | 0 | 2 | 2 | 4.76 | .329 | 1.41 | 9.5 | 3.2 | 9.5 | 17.0 | 18 | 9 | 9 | 4 | 6 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.18 |
| RP | Robles, H.Robles, Hansel >> | 24 | 2015 | R | 39 | 13 | 0 | 0 | 1 | 2.00 | .217 | 0.83 | 5.5 | 2.0 | 7.5 | 18.0 | 11 | 4 | 4 | 2 | 4 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.44 |