| SP | Simmons, C.Simmons, Curt >> | 28 | 1957 | L | 30 | 19 | 19 | 6 | 7 | 5.18 | .337 | 1.50 | 9.4 | 4.1 | 5.5 | 123.1 | 129 | 76 | 71 | 16 | 56 | 75 | 1 | 0 | 0 | 0 | 6 | 3 | 2 | 4.91 |
| SP | Perez, O.Perez, Odalis >> | 30 | 2007 | L | 5 | 22 | 22 | 2 | 13 | 7.54 | .381 | 1.84 | 12.8 | 3.8 | 6.3 | 105.0 | 149 | 90 | 88 | 20 | 44 | 73 | 0 | 0 | 0 | 0 | 5 | 1 | 3 | 5.37 |
| SP | Seaton, T.Seaton, Tom # >> | 25 | 1912 | R | 26 | 32 | 31 | 9 | 14 | 6.30 | .363 | 1.67 | 10.5 | 4.6 | 5.2 | 171.1 | 199 | 141 | 120 | 32 | 87 | 98 | 0 | 0 | 0 | 0 | 7 | 7 | 8 | 5.94 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 34 | 2014 | R | 66 | 58 | 0 | 3 | 5 | 4.90 | .329 | 1.46 | 9.8 | 3.3 | 5.7 | 68.0 | 74 | 41 | 37 | 9 | 25 | 43 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 4.60 |
| RP | Farrell, T.Farrell, Turk >> | 26 | 1960 | R | 25 | 94 | 0 | 5 | 1 | 3.95 | .336 | 1.51 | 10.0 | 3.7 | 5.6 | 118.1 | 131 | 58 | 52 | 17 | 48 | 74 | 0 | 1 | 3 | 0 | 0 | 1 | 3 | 4.86 |
| RP | Holland, A.Holland, Al >> | 31 | 1983 | L | 48 | 95 | 0 | 3 | 1 | 3.07 | .287 | 1.17 | 6.7 | 3.9 | 9.8 | 70.1 | 52 | 25 | 24 | 5 | 30 | 76 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 3.17 |
| CL | Bottalico, R.Bottalico, Ricky >> | 26 | 1995 | R | 55 | 51 | 0 | 5 | 7 | 2.65 | .279 | 1.13 | 5.1 | 5.2 | 8.7 | 57.2 | 32 | 23 | 17 | 5 | 33 | 55 | 0 | 31 | 0 | 0 | 0 | 2 | 0 | 4.05 |
| RP | Akerfelds, D.Akerfelds, Darrel >> | 28 | 1990 | R | 29 | 34 | 0 | 1 | 1 | 5.24 | .322 | 1.40 | 6.1 | 6.7 | 4.9 | 46.1 | 31 | 29 | 27 | 4 | 34 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 5.33 |