| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 12 | 12 | 2 | 6 | 3.12 | .282 | 1.15 | 7.1 | 3.4 | 9.7 | 80.2 | 63 | 28 | 28 | 10 | 30 | 86 | 1 | 0 | 0 | 0 | 9 | 2 | 0 | 3.68 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 11 | 11 | 2 | 5 | 4.00 | .321 | 1.39 | 9.4 | 3.1 | 4.9 | 83.1 | 87 | 38 | 37 | 6 | 29 | 45 | 2 | 0 | 0 | 0 | 6 | 2 | 0 | 3.98 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 11 | 11 | 4 | 4 | 5.52 | .319 | 1.40 | 9.4 | 3.2 | 5.1 | 62.0 | 65 | 41 | 38 | 6 | 22 | 35 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.19 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 29 | 0 | 1 | 1 | 1.75 | .260 | 1.03 | 6.3 | 3.0 | 9.5 | 36.0 | 25 | 7 | 7 | 4 | 12 | 38 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 3.42 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 25 | 0 | 3 | 1 | 1.64 | .220 | 0.82 | 5.5 | 1.9 | 7.1 | 33.0 | 20 | 6 | 6 | 2 | 7 | 26 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 2.94 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 17 | 0 | 3 | 3 | 3.60 | .306 | 1.32 | 9.4 | 2.5 | 5.4 | 25.0 | 26 | 11 | 10 | 4 | 7 | 15 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.72 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 11 | 0 | 0 | 2 | 4.30 | .313 | 1.23 | 7.1 | 4.5 | 8.4 | 14.2 | 11 | 9 | 7 | 0 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.07 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 6 | 0 | 2 | 0 | 2.25 | .226 | 0.88 | 5.6 | 2.3 | 5.6 | 8.0 | 5 | 2 | 2 | 1 | 2 | 5 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.13 |