| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 9 | 9 | 5 | 3 | 3.34 | .312 | 1.36 | 9.4 | 3.0 | 8.0 | 72.2 | 75 | 27 | 27 | 5 | 24 | 64 | 4 | 0 | 0 | 0 | 6 | 0 | 2 | 3.13 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 8 | 8 | 1 | 3 | 3.72 | .264 | 1.04 | 7.0 | 2.5 | 5.4 | 55.2 | 43 | 26 | 23 | 4 | 15 | 33 | 1 | 0 | 0 | 0 | 4 | 2 | 0 | 3.67 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 8 | 8 | 3 | 4 | 5.53 | .321 | 1.40 | 10.3 | 2.4 | 6.0 | 57.0 | 65 | 38 | 35 | 10 | 15 | 38 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.79 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 8 | 8 | 1 | 4 | 6.02 | .338 | 1.51 | 10.2 | 3.5 | 3.6 | 52.1 | 59 | 36 | 35 | 11 | 20 | 21 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 6.15 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 8 | 8 | 3 | 2 | 4.08 | .309 | 1.34 | 10.0 | 2.1 | 3.8 | 64.0 | 71 | 32 | 29 | 7 | 15 | 27 | 3 | 0 | 0 | 0 | 4 | 0 | 0 | 4.28 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 23 | 0 | 5 | 0 | 0.49 | .179 | 0.65 | 5.0 | 1.0 | 9.5 | 18.1 | 10 | 1 | 1 | 0 | 2 | 19 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 1.22 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 16 | 0 | 0 | 0 | 4.61 | .305 | 1.24 | 8.3 | 3.5 | 9.7 | 13.2 | 12 | 7 | 7 | 0 | 5 | 14 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 2.23 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 7 | 0 | 0 | 0 | 3.38 | .351 | 1.63 | 7.9 | 6.8 | 6.8 | 8.0 | 7 | 3 | 3 | 0 | 6 | 6 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.75 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 28 | 0 | 3 | 0 | 1.93 | .311 | 1.36 | 5.8 | 6.4 | 6.4 | 14.0 | 9 | 3 | 3 | 1 | 10 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.64 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 3 | 0 | 1 | 0 | 0.00 | .269 | 1.11 | 7.5 | 3.0 | 12.0 | 6.1 | 5 | 0 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.33 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 6 | 0 | 0 | 1 | 3.38 | .294 | 1.25 | 6.8 | 4.5 | 4.5 | 8.0 | 6 | 4 | 3 | 0 | 4 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 6 | 1 | 1 | 1 | 7.00 | .393 | 1.89 | 13.5 | 3.5 | 4.0 | 18.0 | 27 | 14 | 14 | 4 | 7 | 8 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.33 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 2 | 0 | 0 | 1 | 9.00 | .625 | 5.00 | 36.0 | 9.0 | 0.0 | 1.0 | 4 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |