| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 12 | 12 | 2 | 4 | 4.90 | .323 | 1.42 | 9.2 | 3.6 | 7.6 | 75.1 | 77 | 41 | 41 | 8 | 30 | 63 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 3.95 |
| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 13 | 12 | 3 | 9 | 5.31 | .324 | 1.43 | 9.8 | 3.2 | 8.3 | 84.2 | 91 | 51 | 50 | 12 | 30 | 77 | 4 | 0 | 0 | 0 | 3 | 1 | 0 | 4.13 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 11 | 11 | 4 | 5 | 4.98 | .339 | 1.54 | 10.2 | 3.6 | 4.7 | 65.0 | 74 | 39 | 36 | 10 | 26 | 34 | 2 | 0 | 0 | 0 | 6 | 0 | 0 | 5.15 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 11 | 11 | 4 | 3 | 6.02 | .319 | 1.41 | 9.8 | 2.9 | 6.3 | 43.1 | 47 | 29 | 29 | 7 | 14 | 30 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.70 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 34 | 0 | 3 | 0 | 2.81 | .317 | 1.39 | 8.6 | 4.2 | 9.7 | 41.2 | 39 | 13 | 13 | 3 | 19 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.20 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 31 | 0 | 2 | 2 | 4.03 | .280 | 1.14 | 7.0 | 3.5 | 7.6 | 44.2 | 34 | 25 | 20 | 4 | 17 | 37 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 3.73 |
| SU | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 27 | 0 | 1 | 1 | 1.87 | .252 | 1.01 | 5.7 | 3.5 | 10.1 | 33.2 | 21 | 7 | 7 | 0 | 13 | 37 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.94 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 32 | 0 | 2 | 0 | 2.74 | .297 | 1.27 | 7.5 | 4.1 | 9.2 | 42.2 | 35 | 13 | 13 | 3 | 19 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.24 |