| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 12 | 12 | 7 | 2 | 3.43 | .274 | 1.12 | 8.9 | 1.3 | 5.4 | 78.2 | 77 | 32 | 30 | 9 | 11 | 47 | 1 | 0 | 0 | 0 | 8 | 1 | 2 | 3.76 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 12 | 12 | 6 | 5 | 4.75 | .273 | 1.11 | 7.1 | 2.9 | 5.4 | 72.0 | 57 | 38 | 38 | 7 | 23 | 43 | 2 | 0 | 0 | 1 | 5 | 1 | 1 | 4.07 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 11 | 3 | 6 | 6.25 | .370 | 1.76 | 10.8 | 5.0 | 4.0 | 59.0 | 71 | 43 | 41 | 10 | 33 | 26 | 0 | 0 | 0 | 0 | 5 | 0 | 4 | 6.00 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 30 | 0 | 0 | 1 | 1.79 | .244 | 0.94 | 4.3 | 4.3 | 9.2 | 40.1 | 19 | 8 | 8 | 2 | 19 | 41 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 3.10 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 29 | 0 | 2 | 3 | 3.47 | .259 | 1.05 | 6.5 | 3.0 | 8.8 | 36.1 | 26 | 14 | 14 | 5 | 12 | 35 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.86 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 20 | 0 | 1 | 3 | 7.36 | .353 | 1.64 | 9.8 | 4.9 | 8.6 | 22.0 | 24 | 18 | 18 | 4 | 12 | 21 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.09 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 13 | 0 | 1 | 3 | 7.53 | .348 | 1.60 | 10.3 | 4.5 | 6.4 | 14.1 | 16 | 12 | 12 | 3 | 7 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.86 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 10 | 0 | 1 | 1 | 6.08 | .298 | 1.28 | 8.3 | 3.5 | 6.9 | 13.1 | 12 | 9 | 9 | 3 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.62 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 8 | 0 | 0 | 0 | 7.04 | .324 | 1.43 | 11.6 | 2.6 | 10.3 | 7.2 | 9 | 6 | 6 | 3 | 2 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.14 |