| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 7 | 7 | 4 | 1 | 3.05 | .273 | 1.13 | 8.0 | 2.3 | 5.7 | 44.1 | 39 | 19 | 15 | 4 | 11 | 28 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.66 |
| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 7 | 7 | 0 | 4 | 6.38 | .317 | 1.39 | 10.5 | 2.3 | 7.5 | 36.2 | 42 | 27 | 26 | 6 | 9 | 30 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 4.25 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 7 | 7 | 0 | 2 | 4.10 | .290 | 1.22 | 7.9 | 3.3 | 4.8 | 41.2 | 36 | 20 | 19 | 5 | 15 | 22 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 4.61 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 5 | 5 | 2 | 1 | 4.62 | .248 | 0.91 | 6.1 | 2.2 | 9.0 | 25.1 | 17 | 13 | 13 | 4 | 6 | 25 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 4.04 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 18 | 0 | 2 | 3 | 2.49 | .323 | 1.43 | 9.9 | 3.4 | 9.0 | 21.2 | 23 | 7 | 6 | 1 | 8 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.76 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 16 | 0 | 2 | 1 | 2.42 | .163 | 0.54 | 4.1 | 0.8 | 9.4 | 22.1 | 10 | 6 | 6 | 1 | 2 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1.91 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 14 | 0 | 1 | 0 | 2.00 | .299 | 1.28 | 8.0 | 3.5 | 11.0 | 18.0 | 16 | 4 | 4 | 2 | 7 | 22 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.17 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 5 | 0 | 1 | 0 | 1.42 | .174 | 0.63 | 1.5 | 4.5 | 7.5 | 6.1 | 1 | 1 | 1 | 0 | 3 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 8 | 0 | 1 | 1 | 1.13 | .314 | 1.38 | 6.8 | 5.6 | 7.9 | 8.0 | 6 | 2 | 1 | 1 | 5 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 6 | 0 | 0 | 0 | 6.43 | .344 | 1.57 | 11.6 | 2.6 | 11.6 | 7.0 | 9 | 5 | 5 | 1 | 2 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.14 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 5 | 0 | 0 | 0 | 3.58 | .357 | 1.59 | 11.0 | 3.7 | 5.3 | 27.2 | 33 | 13 | 11 | 4 | 11 | 16 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.19 |