| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 93 | 32 | 32 | 7 | 17 | 4.45 | .305 | 1.30 | 8.8 | 2.9 | 6.9 | 232.1 | 227 | 115 | 115 | 36 | 74 | 179 | 6 | 0 | 0 | 0 | 15 | 5 | 7 | 4.50 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 31 | 31 | 9 | 17 | 5.78 | .341 | 1.49 | 10.4 | 3.0 | 6.4 | 183.2 | 212 | 119 | 118 | 33 | 61 | 130 | 0 | 0 | 0 | 0 | 12 | 12 | 1 | 5.12 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 21 | 1981 | L | 60 | 29 | 29 | 9 | 11 | 5.37 | .362 | 1.67 | 10.0 | 5.1 | 7.5 | 187.2 | 207 | 123 | 112 | 25 | 107 | 156 | 1 | 0 | 0 | 0 | 11 | 6 | 6 | 4.88 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 31 | 31 | 7 | 13 | 5.08 | .326 | 1.42 | 9.2 | 3.7 | 6.0 | 219.2 | 224 | 132 | 124 | 29 | 89 | 147 | 7 | 0 | 0 | 0 | 13 | 6 | 4 | 4.68 |
| SP | Messersmith, A.Messersmith, Andy >> | 30 | 1975 | R | 40 | 30 | 30 | 7 | 17 | 5.58 | .324 | 1.41 | 8.6 | 4.1 | 6.4 | 204.2 | 195 | 128 | 127 | 30 | 93 | 146 | 7 | 0 | 0 | 2 | 13 | 6 | 4 | 4.94 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 93 | 88 | 0 | 7 | 4 | 3.52 | .269 | 1.06 | 6.8 | 2.8 | 10.3 | 117.2 | 88 | 49 | 46 | 17 | 37 | 134 | 0 | 10 | 4 | 0 | 0 | 5 | 1 | 3.68 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 55 | 33 | 0 | 0 | 7 | 3.48 | .266 | 1.09 | 6.6 | 3.3 | 4.8 | 41.1 | 30 | 17 | 16 | 6 | 15 | 22 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 4.93 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 33 | 22 | 0 | 0 | 2 | 4.15 | .343 | 1.52 | 9.4 | 4.7 | 9.0 | 21.2 | 22 | 11 | 10 | 4 | 11 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.19 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 24 | 0 | 0 | 1 | 4.02 | .319 | 1.37 | 10.2 | 2.3 | 8.7 | 31.1 | 35 | 14 | 14 | 5 | 8 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.03 |