| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 7 | 7 | 6 | 1 | 2.57 | .279 | 1.13 | 6.6 | 3.5 | 7.1 | 56.0 | 41 | 16 | 16 | 3 | 22 | 44 | 1 | 0 | 0 | 0 | 5 | 2 | 1 | 3.41 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 6 | 6 | 2 | 1 | 3.83 | .302 | 1.28 | 8.2 | 3.3 | 6.3 | 47.0 | 43 | 21 | 20 | 4 | 17 | 33 | 2 | 0 | 0 | 1 | 2 | 1 | 1 | 3.85 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 6 | 6 | 2 | 2 | 5.70 | .316 | 1.38 | 9.9 | 2.8 | 6.9 | 42.2 | 46 | 31 | 27 | 10 | 13 | 32 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 5.50 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 65 | 6 | 6 | 2 | 3 | 6.27 | .360 | 1.69 | 11.4 | 3.9 | 7.8 | 37.1 | 47 | 26 | 26 | 8 | 16 | 32 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 5.38 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 19 | 0 | 3 | 0 | 1.95 | .231 | 0.90 | 5.0 | 3.3 | 8.3 | 27.2 | 15 | 6 | 6 | 3 | 10 | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.70 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 12 | 0 | 0 | 1 | 1.32 | .281 | 1.10 | 5.5 | 4.8 | 13.2 | 13.2 | 8 | 2 | 2 | 1 | 7 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.92 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 6 | 0 | 0 | 0 | 11.25 | .333 | 1.50 | 6.8 | 6.8 | 15.8 | 4.0 | 3 | 6 | 5 | 0 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.75 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 5 | 0 | 0 | 0 | 5.40 | .483 | 2.80 | 14.4 | 10.8 | 14.4 | 5.0 | 8 | 3 | 3 | 0 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.40 |