| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 19 | 19 | 8 | 5 | 2.90 | .298 | 1.24 | 7.1 | 4.1 | 10.3 | 124.0 | 98 | 40 | 40 | 10 | 56 | 142 | 1 | 0 | 0 | 1 | 13 | 4 | 2 | 3.21 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 77 | 19 | 19 | 2 | 12 | 6.44 | .362 | 1.67 | 11.7 | 3.3 | 8.8 | 95.0 | 124 | 69 | 68 | 15 | 35 | 93 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.29 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 72 | 18 | 18 | 9 | 6 | 5.13 | .331 | 1.45 | 10.7 | 2.5 | 6.3 | 98.1 | 116 | 59 | 56 | 18 | 27 | 69 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.90 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 65 | 18 | 18 | 6 | 7 | 6.47 | .342 | 1.53 | 10.3 | 3.5 | 5.5 | 97.1 | 111 | 70 | 70 | 13 | 38 | 59 | 1 | 0 | 0 | 0 | 5 | 3 | 3 | 4.79 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 40 | 0 | 0 | 1 | 3.65 | .318 | 1.38 | 9.6 | 2.9 | 9.8 | 44.1 | 47 | 18 | 18 | 7 | 14 | 48 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 3.91 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 77 | 31 | 0 | 0 | 2 | 1.65 | .260 | 1.03 | 6.3 | 3.1 | 9.6 | 43.2 | 30 | 14 | 8 | 3 | 15 | 46 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 2.88 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 60 | 18 | 0 | 0 | 0 | 6.16 | .374 | 1.74 | 10.9 | 4.7 | 7.1 | 19.0 | 23 | 14 | 13 | 3 | 10 | 15 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 5.21 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 15 | 0 | 0 | 1 | 7.63 | .361 | 1.70 | 12.0 | 3.6 | 10.8 | 15.1 | 20 | 13 | 13 | 4 | 6 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.27 |