| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 7 | 7 | 2 | 0 | 2.47 | .237 | 0.93 | 6.1 | 2.3 | 9.8 | 47.1 | 32 | 14 | 13 | 3 | 12 | 51 | 1 | 0 | 0 | 1 | 5 | 0 | 0 | 2.43 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 5 | 5 | 2 | 0 | 4.97 | .350 | 1.58 | 8.3 | 6.1 | 10.1 | 25.1 | 23 | 14 | 14 | 6 | 17 | 28 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.04 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 49 | 6 | 6 | 3 | 0 | 3.89 | .246 | 0.98 | 7.1 | 1.9 | 10.1 | 34.2 | 27 | 15 | 15 | 6 | 7 | 38 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 3.68 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 69 | 7 | 0 | 0 | 0 | 3.52 | .378 | 1.83 | 12.9 | 5.1 | 11.6 | 7.2 | 10 | 6 | 3 | 2 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.86 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 77 | 13 | 0 | 3 | 2 | 2.16 | .275 | 1.08 | 8.4 | 1.7 | 11.8 | 16.2 | 15 | 4 | 4 | 0 | 3 | 21 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1.13 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 22 | 2004 | R | 52 | 13 | 0 | 2 | 0 | 3.38 | .250 | 0.94 | 4.5 | 3.9 | 7.3 | 16.0 | 8 | 6 | 6 | 2 | 7 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.50 |
| SU | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 15 | 0 | 1 | 0 | 2.55 | .243 | 0.96 | 4.8 | 4.2 | 9.0 | 17.2 | 9 | 8 | 5 | 1 | 8 | 17 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.18 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 18 | 0 | 0 | 1 | 2.57 | .250 | 0.95 | 6.0 | 2.6 | 11.6 | 21.0 | 14 | 6 | 6 | 1 | 6 | 27 | 0 | 12 | 1 | 0 | 0 | 1 | 3 | 2.05 |
| SP | Appier, K.Appier, Kevin >> | 26 | 1993 | R | 31 | 3 | 1 | 2 | 0 | 1.59 | .209 | 0.79 | 4.9 | 2.5 | 7.4 | 11.1 | 6 | 2 | 2 | 0 | 3 | 9 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 2.18 |