| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 31 | 31 | 16 | 10 | 3.93 | .294 | 1.21 | 8.8 | 2.2 | 9.3 | 238.0 | 232 | 108 | 104 | 43 | 57 | 246 | 6 | 0 | 0 | 1 | 15 | 8 | 9 | 4.10 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 31 | 31 | 9 | 8 | 5.99 | .338 | 1.49 | 10.1 | 3.3 | 9.6 | 174.1 | 196 | 123 | 116 | 35 | 63 | 185 | 0 | 0 | 0 | 0 | 11 | 8 | 5 | 4.71 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 31 | 30 | 12 | 13 | 5.58 | .341 | 1.54 | 10.3 | 3.6 | 7.3 | 175.2 | 201 | 120 | 109 | 32 | 70 | 141 | 0 | 0 | 0 | 0 | 10 | 2 | 5 | 5.00 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 89 | 0 | 9 | 5 | 3.28 | .271 | 1.08 | 5.5 | 4.2 | 9.3 | 140.0 | 86 | 54 | 51 | 24 | 65 | 145 | 0 | 11 | 4 | 0 | 0 | 5 | 0 | 4.66 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 69 | 0 | 3 | 7 | 3.41 | .283 | 1.17 | 7.3 | 3.2 | 11.4 | 87.0 | 71 | 35 | 33 | 14 | 31 | 110 | 0 | 9 | 3 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 81 | 60 | 0 | 4 | 2 | 2.40 | .269 | 1.09 | 7.4 | 2.5 | 10.1 | 82.1 | 67 | 22 | 22 | 6 | 23 | 92 | 0 | 11 | 2 | 0 | 0 | 1 | 0 | 2.59 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 73 | 38 | 0 | 2 | 4 | 7.20 | .308 | 1.33 | 9.0 | 3.0 | 10.5 | 30.0 | 30 | 24 | 24 | 8 | 10 | 35 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 5.13 |