| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 18 | 18 | 8 | 6 | 4.01 | .292 | 1.23 | 8.3 | 2.8 | 5.1 | 134.2 | 123 | 69 | 60 | 14 | 42 | 76 | 3 | 0 | 0 | 0 | 11 | 2 | 2 | 4.21 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 17 | 17 | 7 | 5 | 5.90 | .335 | 1.49 | 10.0 | 3.4 | 7.5 | 103.2 | 115 | 74 | 68 | 18 | 39 | 86 | 0 | 0 | 0 | 0 | 8 | 3 | 7 | 4.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 17 | 17 | 4 | 9 | 5.21 | .336 | 1.52 | 9.2 | 4.5 | 5.4 | 114.0 | 116 | 70 | 66 | 16 | 57 | 68 | 0 | 0 | 0 | 0 | 7 | 0 | 4 | 5.13 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 42 | 0 | 1 | 2 | 3.43 | .222 | 0.84 | 4.7 | 2.9 | 6.9 | 63.0 | 33 | 25 | 24 | 5 | 20 | 48 | 0 | 8 | 1 | 0 | 0 | 1 | 3 | 3.51 |
| RP | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 87 | 39 | 0 | 6 | 1 | 2.93 | .283 | 1.16 | 7.1 | 3.3 | 10.0 | 43.0 | 34 | 14 | 14 | 4 | 16 | 48 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.16 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 31 | 0 | 2 | 0 | 2.50 | .285 | 1.17 | 7.0 | 3.5 | 9.5 | 36.0 | 28 | 13 | 10 | 4 | 14 | 38 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.58 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 22 | 0 | 1 | 2 | 2.00 | .250 | 0.96 | 6.7 | 2.0 | 9.0 | 27.0 | 20 | 6 | 6 | 2 | 6 | 27 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.74 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 18 | 0 | 0 | 1 | 6.35 | .386 | 1.88 | 12.2 | 4.8 | 6.9 | 17.0 | 23 | 14 | 12 | 3 | 9 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.35 |