| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 18 | 18 | 8 | 3 | 2.60 | .243 | 0.95 | 6.9 | 1.6 | 9.6 | 121.1 | 93 | 35 | 35 | 11 | 22 | 129 | 0 | 0 | 0 | 0 | 14 | 2 | 0 | 2.64 |
| SP | Gibson, B.Gibson, Bob † >> | 33 | 1968 | R | 93 | 18 | 18 | 13 | 3 | 3.33 | .266 | 1.05 | 7.2 | 2.3 | 5.1 | 135.0 | 108 | 51 | 50 | 8 | 34 | 76 | 5 | 0 | 0 | 0 | 12 | 5 | 3 | 3.51 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 15 | 15 | 6 | 5 | 3.46 | .278 | 1.14 | 7.4 | 2.9 | 4.4 | 96.1 | 79 | 39 | 37 | 9 | 31 | 47 | 1 | 0 | 0 | 0 | 9 | 1 | 2 | 4.24 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 17 | 17 | 7 | 5 | 4.47 | .302 | 1.30 | 7.8 | 4.0 | 7.9 | 102.2 | 88 | 56 | 51 | 8 | 45 | 90 | 2 | 0 | 0 | 0 | 8 | 0 | 1 | 3.58 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 39 | 0 | 4 | 1 | 3.22 | .306 | 1.32 | 8.2 | 3.9 | 5.3 | 44.2 | 40 | 18 | 16 | 3 | 19 | 26 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 15 | 0 | 1 | 0 | 2.08 | .316 | 1.38 | 4.2 | 8.5 | 9.0 | 17.1 | 8 | 4 | 4 | 0 | 16 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.82 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 11 | 0 | 0 | 0 | 6.39 | .345 | 1.58 | 9.0 | 6.0 | 9.8 | 12.2 | 12 | 9 | 9 | 5 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.25 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 11 | 0 | 0 | 0 | 4.50 | .321 | 1.33 | 9.8 | 2.3 | 7.5 | 12.0 | 13 | 8 | 6 | 1 | 3 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.42 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 44 | 0 | 2 | 0 | 3.51 | .272 | 1.10 | 7.0 | 2.9 | 8.1 | 41.0 | 32 | 18 | 16 | 1 | 13 | 37 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 2.54 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 44 | 0 | 2 | 5 | 3.59 | .234 | 0.91 | 5.8 | 2.6 | 8.6 | 42.2 | 27 | 17 | 17 | 3 | 12 | 40 | 0 | 30 | 2 | 0 | 0 | 0 | 1 | 2.88 |