| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 34 | 34 | 21 | 4 | 2.74 | .255 | 1.02 | 6.6 | 2.5 | 8.0 | 220.0 | 162 | 72 | 67 | 14 | 62 | 196 | 3 | 0 | 0 | 2 | 23 | 2 | 0 | 2.92 |
| SP | Maddux, G.Maddux, Greg † # >> | 29 | 1995 | R | 89 | 31 | 31 | 18 | 4 | 3.35 | .271 | 1.10 | 8.8 | 1.1 | 5.0 | 209.2 | 204 | 90 | 78 | 21 | 26 | 116 | 6 | 0 | 0 | 1 | 20 | 4 | 4 | 3.63 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 72 | 0 | 7 | 2 | 3.29 | .279 | 1.15 | 6.5 | 3.9 | 4.8 | 93.0 | 67 | 35 | 34 | 7 | 40 | 50 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.23 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 58 | 0 | 6 | 0 | 3.48 | .307 | 1.30 | 6.0 | 5.8 | 8.6 | 64.2 | 43 | 27 | 25 | 6 | 41 | 61 | 0 | 1 | 1 | 0 | 0 | 2 | 4 | 4.33 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 40 | 0 | 3 | 1 | 3.02 | .287 | 1.21 | 5.7 | 5.3 | 9.6 | 44.2 | 28 | 15 | 15 | 3 | 26 | 47 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.52 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 41 | 0 | 4 | 2 | 4.37 | .283 | 1.19 | 7.5 | 3.3 | 8.5 | 55.2 | 46 | 28 | 27 | 9 | 20 | 52 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 4.33 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 66 | 0 | 3 | 0 | 1.67 | .228 | 0.87 | 5.7 | 2.2 | 7.7 | 70.0 | 44 | 15 | 13 | 5 | 17 | 60 | 0 | 44 | 4 | 0 | 0 | 1 | 1 | 2.99 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 16 | 3 | 4 | 3 | 3.54 | .304 | 1.31 | 7.4 | 4.5 | 9.1 | 68.2 | 56 | 27 | 27 | 7 | 34 | 69 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 3.81 |