| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 7 | 7 | 4 | 2 | 2.43 | .234 | 0.90 | 6.1 | 2.1 | 8.2 | 55.2 | 37 | 15 | 15 | 4 | 13 | 50 | 4 | 0 | 0 | 2 | 5 | 1 | 0 | 2.89 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 6 | 6 | 0 | 5 | 10.17 | .400 | 1.96 | 14.9 | 2.7 | 9.0 | 23.0 | 38 | 30 | 26 | 9 | 7 | 23 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 7.13 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 6 | 6 | 1 | 2 | 5.46 | .338 | 1.53 | 10.2 | 3.8 | 6.1 | 31.1 | 35 | 22 | 19 | 2 | 13 | 21 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 3.74 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 7 | 6 | 1 | 4 | 5.62 | .356 | 1.63 | 10.5 | 4.4 | 6.8 | 41.2 | 48 | 32 | 26 | 4 | 20 | 31 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 4.29 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 15 | 0 | 2 | 0 | 2.86 | .283 | 1.14 | 6.5 | 3.7 | 7.4 | 22.0 | 16 | 7 | 7 | 1 | 9 | 18 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.32 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 15 | 0 | 0 | 0 | 5.40 | .286 | 1.20 | 6.6 | 4.2 | 13.2 | 15.0 | 11 | 9 | 9 | 1 | 7 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.33 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 12 | 0 | 1 | 1 | 3.06 | .254 | 0.96 | 5.8 | 3.2 | 11.1 | 17.2 | 11 | 6 | 6 | 2 | 6 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.29 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 12 | 0 | 1 | 3 | 4.50 | .423 | 2.10 | 11.7 | 7.2 | 11.7 | 10.0 | 13 | 8 | 5 | 1 | 8 | 13 | 0 | 0 | 2 | 0 | 0 | 1 | 2 | 4.40 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 9 | 0 | 1 | 0 | 5.63 | .429 | 2.25 | 11.3 | 9.0 | 10.1 | 8.0 | 10 | 7 | 5 | 1 | 8 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 5.38 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 0.0 | 9.0 | 0.0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 4 | 0 | 0 | 0 | 5.06 | .385 | 1.88 | 12.6 | 5.4 | 3.6 | 5.1 | 7 | 3 | 3 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |