| SP | Buchholz, C.Buchholz, Clay >> | 34 | 2018 | R | 52 | 22 | 22 | 6 | 12 | 4.45 | .319 | 1.39 | 9.6 | 3.0 | 5.5 | 141.2 | 150 | 82 | 70 | 23 | 47 | 86 | 0 | 0 | 0 | 0 | 12 | 2 | 5 | 4.94 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 49 | 20 | 20 | 4 | 10 | 5.27 | .327 | 1.44 | 9.2 | 3.8 | 6.1 | 97.1 | 99 | 60 | 57 | 15 | 41 | 66 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.98 |
| SP | Kelly, M.Kelly, Merrill >> | 33 | 2022 | R | 38 | 22 | 22 | 2 | 14 | 6.09 | .352 | 1.62 | 10.9 | 3.7 | 6.9 | 125.2 | 151 | 88 | 85 | 24 | 52 | 96 | 1 | 0 | 0 | 0 | 8 | 2 | 3 | 5.26 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2008 | L | 34 | 20 | 20 | 1 | 12 | 6.20 | .341 | 1.53 | 10.7 | 3.1 | 6.4 | 119.0 | 141 | 82 | 82 | 25 | 41 | 84 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 5.43 |
| SP | Webb, B.Webb, Brandon # >> | 25 | 2004 | R | 20 | 21 | 20 | 4 | 11 | 4.66 | .328 | 1.43 | 9.0 | 4.0 | 6.0 | 125.2 | 125 | 67 | 65 | 12 | 55 | 83 | 0 | 0 | 0 | 0 | 10 | 4 | 5 | 4.34 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 68 | 67 | 0 | 1 | 1 | 2.53 | .279 | 1.16 | 6.4 | 4.1 | 8.8 | 92.1 | 65 | 33 | 26 | 6 | 42 | 90 | 0 | 4 | 2 | 0 | 0 | 0 | 3 | 3.26 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 59 | 60 | 0 | 2 | 6 | 4.75 | .327 | 1.43 | 9.2 | 3.7 | 4.1 | 77.2 | 79 | 46 | 41 | 11 | 32 | 35 | 0 | 4 | 3 | 0 | 0 | 2 | 2 | 5.27 |
| RP | Bradley, A.Bradley, Archie >> | 24 | 2017 | R | 57 | 50 | 0 | 7 | 3 | 3.23 | .270 | 1.09 | 6.6 | 3.2 | 8.3 | 61.1 | 45 | 24 | 22 | 7 | 22 | 56 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.79 |
| RP | Valverde, J.Valverde, Jose >> | 28 | 2007 | R | 50 | 41 | 0 | 2 | 3 | 2.65 | .285 | 1.14 | 5.1 | 5.1 | 9.9 | 51.0 | 29 | 15 | 15 | 3 | 29 | 56 | 0 | 4 | 2 | 0 | 0 | 3 | 1 | 3.45 |
| RP | Villarreal, O.Villarreal, Oscar >> | 22 | 2003 | R | 29 | 32 | 0 | 1 | 2 | 5.66 | .319 | 1.33 | 7.0 | 5.0 | 6.4 | 41.1 | 32 | 26 | 26 | 7 | 23 | 29 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 5.71 |