| SP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 100 | 35 | 35 | 0 | 8 | 5.64 | .349 | 1.60 | 9.7 | 4.8 | 10.9 | 81.1 | 87 | 57 | 51 | 9 | 43 | 98 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.65 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 86 | 34 | 34 | 10 | 10 | 4.96 | .322 | 1.41 | 10.1 | 2.6 | 8.6 | 199.2 | 224 | 113 | 110 | 30 | 58 | 190 | 0 | 0 | 0 | 0 | 14 | 2 | 3 | 3.95 |
| SP | Paddack, C.Paddack, Chris # >> | 23 | 2019 | R | 80 | 33 | 33 | 10 | 6 | 4.87 | .307 | 1.31 | 9.4 | 2.5 | 9.7 | 175.2 | 182 | 95 | 95 | 25 | 48 | 188 | 0 | 0 | 0 | 0 | 13 | 3 | 4 | 3.58 |
| SP | Jones, R.Jones, Randy # >> | 26 | 1976 | L | 49 | 33 | 32 | 17 | 11 | 4.00 | .300 | 1.27 | 9.3 | 2.1 | 5.2 | 218.1 | 226 | 99 | 97 | 21 | 52 | 126 | 12 | 0 | 0 | 4 | 16 | 3 | 0 | 3.85 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 95 | 84 | 0 | 10 | 1 | 3.55 | .290 | 1.20 | 6.5 | 4.4 | 9.3 | 111.2 | 80 | 45 | 44 | 13 | 54 | 115 | 0 | 6 | 1 | 0 | 0 | 3 | 0 | 3.99 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 89 | 77 | 0 | 6 | 3 | 2.89 | .277 | 1.13 | 6.8 | 3.4 | 8.8 | 96.2 | 73 | 33 | 31 | 8 | 36 | 94 | 0 | 8 | 1 | 0 | 0 | 2 | 6 | 3.31 |
| RP | Meredith, C.Meredith, Cla >> | 23 | 2006 | R | 76 | 78 | 0 | 7 | 4 | 4.84 | .333 | 1.49 | 10.6 | 2.9 | 6.1 | 96.2 | 113 | 52 | 52 | 11 | 31 | 65 | 0 | 7 | 7 | 0 | 0 | 1 | 0 | 4.14 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 56 | 0 | 3 | 9 | 6.00 | .339 | 1.54 | 9.9 | 4.0 | 7.6 | 63.0 | 69 | 45 | 42 | 10 | 28 | 53 | 0 | 6 | 4 | 0 | 0 | 0 | 0 | 4.71 |
| RP | Andersen, L.Andersen, Larry >> | 39 | 1992 | R | 54 | 52 | 0 | 3 | 2 | 4.21 | .350 | 1.62 | 10.6 | 4.1 | 9.7 | 51.1 | 60 | 26 | 24 | 8 | 23 | 55 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.24 |
| SP | Pivetta, N.Pivetta, Nick >> | 32 | 2025 | R | 82 | 33 | 32 | 11 | 10 | 5.38 | .332 | 1.46 | 10.1 | 3.0 | 8.5 | 169.0 | 190 | 103 | 101 | 26 | 56 | 159 | 0 | 0 | 0 | 0 | 15 | 6 | 3 | 4.22 |