| SP | Romo, V.Romo, Vicente # >> | 25 | 1968 | R | 94 | 38 | 38 | 0 | 6 | 3.84 | .301 | 1.24 | 7.3 | 3.9 | 5.5 | 98.1 | 80 | 42 | 42 | 9 | 42 | 60 | 0 | 0 | 0 | 0 | 1 | 5 | 2 | 4.41 |
| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 98 | 37 | 37 | 27 | 8 | 3.27 | .291 | 1.20 | 7.1 | 3.7 | 8.1 | 281.0 | 223 | 106 | 102 | 26 | 115 | 254 | 10 | 0 | 0 | 2 | 25 | 8 | 5 | 3.71 |
| SP | Bieber, S.Bieber, Shane >> | 25 | 2020 | R | 100 | 36 | 36 | 0 | 1 | 1.73 | .246 | 0.96 | 5.0 | 3.6 | 8.9 | 104.0 | 58 | 20 | 20 | 4 | 42 | 103 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2.79 |
| SP | Siebert, S.Siebert, Sonny † # >> | 31 | 1968 | R | 52 | 34 | 34 | 20 | 8 | 3.95 | .312 | 1.34 | 8.0 | 4.1 | 5.2 | 234.2 | 208 | 110 | 103 | 23 | 106 | 135 | 4 | 0 | 0 | 1 | 20 | 5 | 4 | 4.55 |
| SP | Tomlin, J.Tomlin, Josh >> | 30 | 2015 | R | 92 | 31 | 31 | 0 | 2 | 2.61 | .285 | 1.18 | 8.1 | 2.6 | 5.3 | 86.1 | 77 | 25 | 25 | 4 | 25 | 51 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.33 |
| RP | Perez, O.Perez, Oliver >> | 37 | 2018 | L | 91 | 96 | 0 | 9 | 3 | 2.88 | .272 | 1.12 | 7.5 | 2.6 | 8.4 | 140.2 | 117 | 45 | 45 | 8 | 40 | 130 | 0 | 5 | 4 | 0 | 0 | 1 | 5 | 2.76 |
| RP | Manship, J.Manship, Jeff >> | 30 | 2015 | R | 81 | 84 | 0 | 13 | 3 | 3.23 | .262 | 1.06 | 6.3 | 3.2 | 5.3 | 128.0 | 90 | 47 | 46 | 9 | 46 | 76 | 0 | 6 | 5 | 0 | 0 | 0 | 0 | 3.80 |
| RP | Clippard, T.Clippard, Tyler >> | 34 | 2019 | R | 73 | 83 | 0 | 6 | 6 | 3.06 | .280 | 1.16 | 6.8 | 3.6 | 7.3 | 109.0 | 82 | 42 | 37 | 11 | 44 | 89 | 0 | 10 | 1 | 0 | 0 | 1 | 4 | 3.92 |
| RP | Karinchak, J.Karinchak, James >> | 26 | 2022 | R | 60 | 59 | 0 | 4 | 5 | 3.18 | .325 | 1.42 | 6.4 | 6.4 | 10.0 | 70.2 | 50 | 26 | 25 | 2 | 50 | 78 | 0 | 8 | 6 | 0 | 0 | 2 | 7 | 3.37 |
| RP | Kelley, T.Kelley, Tom † >> | 21 | 1965 | R | 45 | 71 | 0 | 37 | 4 | 3.02 | .271 | 1.10 | 6.1 | 3.8 | 8.7 | 185.0 | 125 | 64 | 62 | 13 | 79 | 178 | 0 | 1 | 0 | 0 | 0 | 2 | 13 | 3.30 |
| RP | Sandlin, N.Sandlin, Nick >> | 26 | 2023 | R | 53 | 38 | 0 | 1 | 1 | 2.51 | .243 | 0.96 | 6.1 | 2.7 | 7.6 | 46.2 | 31 | 13 | 13 | 6 | 14 | 39 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Hooper, B.Hooper, Bob # >> | 31 | 1953 | R | 26 | 38 | 0 | 4 | 3 | 4.37 | .352 | 1.63 | 10.3 | 4.4 | 4.0 | 47.1 | 54 | 24 | 23 | 5 | 23 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.96 |