| SP | Buchholz, C.Buchholz, Clay # >> | 34 | 2018 | R | 55 | 33 | 33 | 6 | 21 | 7.19 | .349 | 1.59 | 11.7 | 2.6 | 7.2 | 169.0 | 219 | 136 | 135 | 36 | 49 | 136 | 0 | 0 | 0 | 0 | 10 | 4 | 4 | 5.10 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 52 | 34 | 34 | 6 | 13 | 5.30 | .335 | 1.49 | 9.5 | 3.9 | 6.9 | 156.1 | 165 | 97 | 92 | 26 | 68 | 120 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 4.99 |
| SP | Kelly, M.Kelly, Merrill >> | 33 | 2022 | R | 45 | 32 | 32 | 8 | 10 | 4.33 | .334 | 1.48 | 9.7 | 3.6 | 5.9 | 193.1 | 209 | 101 | 93 | 18 | 78 | 127 | 0 | 0 | 0 | 0 | 15 | 4 | 6 | 4.17 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2008 | L | 35 | 33 | 32 | 6 | 19 | 4.95 | .327 | 1.44 | 10.4 | 2.6 | 6.0 | 194.2 | 224 | 109 | 107 | 30 | 57 | 129 | 3 | 0 | 0 | 0 | 17 | 3 | 7 | 4.61 |
| SP | Webb, B.Webb, Brandon # >> | 25 | 2004 | R | 21 | 34 | 31 | 7 | 15 | 6.29 | .347 | 1.55 | 8.8 | 5.2 | 6.7 | 167.1 | 163 | 120 | 117 | 24 | 97 | 124 | 0 | 0 | 0 | 0 | 12 | 7 | 9 | 5.25 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 56 | 100 | 0 | 8 | 9 | 4.51 | .324 | 1.42 | 7.6 | 5.2 | 9.3 | 139.2 | 118 | 71 | 70 | 22 | 80 | 144 | 0 | 6 | 6 | 0 | 0 | 3 | 4 | 4.78 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 52 | 93 | 0 | 5 | 2 | 4.13 | .308 | 1.31 | 8.3 | 3.5 | 5.8 | 122.0 | 113 | 58 | 56 | 11 | 47 | 79 | 0 | 5 | 3 | 0 | 0 | 3 | 5 | 4.11 |
| RP | Bradley, A.Bradley, Archie >> | 24 | 2017 | R | 44 | 95 | 0 | 4 | 6 | 3.64 | .284 | 1.18 | 7.5 | 3.1 | 8.3 | 121.0 | 101 | 49 | 49 | 11 | 42 | 111 | 0 | 12 | 2 | 0 | 0 | 1 | 0 | 3.41 |
| RP | Valverde, J.Valverde, Jose >> | 28 | 2007 | R | 43 | 79 | 0 | 5 | 3 | 3.65 | .320 | 1.39 | 7.2 | 5.3 | 9.2 | 91.1 | 73 | 38 | 37 | 12 | 54 | 93 | 0 | 2 | 7 | 0 | 0 | 2 | 2 | 4.52 |
| RP | Villarreal, O.Villarreal, Oscar >> | 22 | 2003 | R | 21 | 64 | 0 | 4 | 5 | 3.25 | .301 | 1.28 | 7.7 | 3.8 | 5.9 | 83.0 | 71 | 33 | 30 | 6 | 35 | 54 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.94 |