| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 22 | 22 | 11 | 5 | 3.30 | .267 | 1.08 | 7.1 | 2.7 | 7.8 | 139.0 | 109 | 53 | 51 | 17 | 41 | 120 | 1 | 0 | 0 | 1 | 15 | 2 | 0 | 3.79 |
| SP | Snell, B.Snell, Blake † $$ >> | 25 | 2018 | L | 81 | 21 | 21 | 12 | 6 | 2.80 | .277 | 1.13 | 6.5 | 3.8 | 7.4 | 131.2 | 94 | 43 | 41 | 9 | 55 | 108 | 0 | 0 | 0 | 0 | 15 | 2 | 1 | 3.55 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 21 | 21 | 6 | 6 | 4.37 | .322 | 1.40 | 8.3 | 4.3 | 3.6 | 115.1 | 106 | 56 | 56 | 11 | 55 | 46 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 4.96 |
| SP | Harden, R.Harden, Rich # >> | 27 | 2008 | R | 61 | 21 | 21 | 5 | 6 | 3.43 | .259 | 1.02 | 6.3 | 2.9 | 7.4 | 86.2 | 60 | 37 | 33 | 6 | 28 | 71 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.34 |
| RP | Chapman, A.Chapman, Aroldis $ >> | 26 | 2014 | L | 94 | 66 | 0 | 4 | 1 | 1.89 | .299 | 1.26 | 6.6 | 4.7 | 9.0 | 57.0 | 42 | 12 | 12 | 3 | 30 | 57 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.32 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 68 | 0 | 6 | 0 | 2.75 | .286 | 1.18 | 6.4 | 4.3 | 6.9 | 52.1 | 37 | 16 | 16 | 7 | 25 | 40 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 4.71 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 59 | 0 | 4 | 1 | 4.53 | .297 | 1.27 | 7.8 | 3.8 | 8.4 | 45.2 | 39 | 23 | 23 | 13 | 19 | 42 | 0 | 4 | 3 | 0 | 0 | 0 | 1 | 6.16 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 55 | 0 | 1 | 1 | 1.47 | .241 | 0.91 | 4.2 | 4.0 | 7.5 | 43.0 | 20 | 8 | 7 | 2 | 19 | 36 | 0 | 8 | 0 | 0 | 0 | 2 | 2 | 3.40 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 40 | 0 | 2 | 1 | 4.05 | .355 | 1.65 | 8.7 | 6.6 | 8.0 | 26.2 | 25 | 13 | 12 | 3 | 19 | 23 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.92 |
| RP | LaRoche, D.LaRoche, Dave >> | 28 | 1976 | L | 33 | 31 | 0 | 2 | 2 | 2.83 | .281 | 1.14 | 5.9 | 4.4 | 8.2 | 35.0 | 23 | 12 | 11 | 2 | 17 | 32 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.46 |