| SP | Plesac, Z.Plesac, Zach >> | 25 | 2020 | R | 96 | 23 | 23 | 0 | 5 | 4.60 | .307 | 1.33 | 10.9 | 1.2 | 7.8 | 58.2 | 70 | 30 | 30 | 8 | 8 | 50 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.48 |
| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 94 | 22 | 22 | 13 | 2 | 3.54 | .283 | 1.16 | 6.5 | 4.0 | 8.1 | 162.2 | 117 | 66 | 64 | 12 | 72 | 146 | 9 | 0 | 0 | 5 | 15 | 4 | 0 | 3.57 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 93 | 24 | 24 | 13 | 3 | 2.84 | .277 | 1.13 | 7.6 | 2.5 | 8.6 | 184.0 | 156 | 65 | 58 | 12 | 52 | 175 | 6 | 0 | 0 | 1 | 19 | 4 | 3 | 2.86 |
| SP | Siebert, S.Siebert, Sonny † >> | 31 | 1968 | R | 64 | 22 | 22 | 14 | 5 | 3.31 | .319 | 1.37 | 7.6 | 4.8 | 6.0 | 149.2 | 126 | 63 | 55 | 15 | 79 | 100 | 4 | 0 | 0 | 1 | 13 | 5 | 1 | 4.66 |
| SP | Germano, J.Germano, Justin # >> | 28 | 2010 | R | 62 | 22 | 22 | 0 | 1 | 5.66 | .344 | 1.57 | 10.8 | 3.5 | 7.2 | 41.1 | 49 | 30 | 26 | 8 | 16 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.10 |
| RP | Perez, O.Perez, Oliver † >> | 37 | 2018 | L | 93 | 52 | 0 | 10 | 2 | 3.04 | .252 | 1.01 | 6.9 | 2.2 | 9.1 | 77.0 | 59 | 26 | 26 | 4 | 19 | 78 | 0 | 4 | 2 | 0 | 0 | 0 | 1 | 2.39 |
| RP | Manship, J.Manship, Jeff >> | 30 | 2015 | R | 88 | 50 | 0 | 7 | 5 | 2.95 | .274 | 1.12 | 6.3 | 3.8 | 5.7 | 73.1 | 51 | 28 | 24 | 3 | 31 | 46 | 0 | 5 | 4 | 0 | 0 | 1 | 0 | 3.59 |
| RP | Bieber, S.Bieber, Shane † >> | 25 | 2020 | R | 78 | 47 | 0 | 15 | 5 | 2.56 | .271 | 1.08 | 6.3 | 3.4 | 8.8 | 112.1 | 79 | 32 | 32 | 4 | 42 | 110 | 0 | 2 | 1 | 0 | 0 | 4 | 8 | 2.73 |
| RP | Clippard, T.Clippard, Tyler >> | 34 | 2019 | R | 71 | 40 | 0 | 2 | 3 | 4.01 | .318 | 1.36 | 9.7 | 2.6 | 7.9 | 49.1 | 53 | 24 | 22 | 4 | 14 | 43 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.29 |
| RP | Sandlin, N.Sandlin, Nick >> | 26 | 2023 | R | 48 | 15 | 0 | 0 | 0 | 3.38 | .200 | 0.75 | 5.1 | 1.7 | 5.6 | 16.0 | 9 | 6 | 6 | 4 | 3 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.56 |