| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 24 | 23 | 4 | 13 | 3.65 | .278 | 1.13 | 7.5 | 2.6 | 8.2 | 167.2 | 140 | 72 | 68 | 19 | 49 | 153 | 3 | 0 | 0 | 0 | 14 | 5 | 0 | 3.62 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 23 | 23 | 6 | 12 | 3.25 | .284 | 1.18 | 6.9 | 3.7 | 5.7 | 149.2 | 115 | 61 | 54 | 8 | 61 | 95 | 2 | 0 | 0 | 1 | 15 | 2 | 3 | 3.69 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 85 | 22 | 22 | 5 | 14 | 4.57 | .321 | 1.39 | 9.0 | 3.5 | 6.3 | 143.2 | 143 | 76 | 73 | 18 | 56 | 100 | 5 | 0 | 0 | 1 | 11 | 5 | 8 | 4.52 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 99 | 37 | 0 | 1 | 3 | 3.83 | .302 | 1.30 | 7.4 | 4.3 | 7.0 | 40.0 | 33 | 21 | 17 | 5 | 19 | 31 | 0 | 15 | 4 | 0 | 0 | 0 | 1 | 4.50 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 29 | 2017 | R | 97 | 58 | 0 | 5 | 3 | 4.25 | .308 | 1.28 | 8.4 | 3.1 | 10.9 | 72.0 | 67 | 38 | 34 | 6 | 25 | 87 | 0 | 1 | 0 | 0 | 0 | 4 | 4 | 2.88 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 49 | 0 | 3 | 2 | 1.55 | .251 | 0.99 | 5.9 | 3.1 | 8.3 | 63.2 | 41 | 12 | 11 | 2 | 22 | 58 | 0 | 2 | 1 | 0 | 0 | 1 | 5 | 2.67 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 36 | 0 | 4 | 3 | 4.28 | .306 | 1.33 | 7.7 | 4.3 | 11.3 | 40.0 | 34 | 20 | 19 | 4 | 19 | 50 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.23 |
| RP | Brasier, R.Brasier, Ryan # >> | 30 | 2018 | R | 82 | 33 | 0 | 0 | 2 | 4.46 | .335 | 1.46 | 10.8 | 2.5 | 6.8 | 36.1 | 43 | 26 | 18 | 7 | 10 | 27 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 5.03 |