| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 99 | 25 | 25 | 12 | 5 | 3.33 | .280 | 1.12 | 7.2 | 2.9 | 10.8 | 167.1 | 134 | 63 | 62 | 19 | 54 | 201 | 1 | 0 | 0 | 0 | 18 | 7 | 5 | 3.17 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 82 | 24 | 24 | 7 | 10 | 4.24 | .312 | 1.32 | 8.4 | 3.5 | 8.1 | 153.0 | 143 | 81 | 72 | 24 | 59 | 138 | 2 | 0 | 0 | 0 | 14 | 6 | 7 | 4.51 |
| SP | Bumgarner, M.Bumgarner, Madison >> | 26 | 2016 | L | 76 | 24 | 24 | 9 | 6 | 4.39 | .306 | 1.28 | 8.7 | 2.9 | 9.0 | 153.2 | 148 | 78 | 75 | 28 | 49 | 153 | 0 | 0 | 0 | 0 | 12 | 6 | 2 | 4.46 |
| SP | Iwakuma, H.Iwakuma, Hisashi # >> | 32 | 2013 | R | 65 | 23 | 23 | 11 | 6 | 4.32 | .292 | 1.20 | 8.3 | 2.5 | 6.8 | 145.2 | 134 | 70 | 70 | 24 | 41 | 110 | 2 | 0 | 0 | 0 | 14 | 5 | 5 | 4.59 |
| SP | Syndergaard, N.Syndergaard, Noah >> | 22 | 2015 | R | 56 | 23 | 23 | 5 | 12 | 5.43 | .335 | 1.49 | 10.4 | 3.0 | 10.9 | 121.0 | 140 | 73 | 73 | 28 | 40 | 146 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 4.66 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 71 | 0 | 10 | 0 | 0.89 | .184 | 0.67 | 4.5 | 1.5 | 10.6 | 100.2 | 50 | 10 | 10 | 7 | 17 | 118 | 0 | 15 | 1 | 0 | 0 | 1 | 3 | 2.09 |
| RP | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 85 | 55 | 0 | 6 | 3 | 3.93 | .321 | 1.38 | 7.5 | 4.9 | 11.9 | 55.0 | 46 | 25 | 24 | 6 | 30 | 73 | 0 | 11 | 2 | 0 | 0 | 2 | 0 | 3.51 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 74 | 38 | 0 | 3 | 4 | 3.97 | .240 | 0.90 | 5.4 | 2.8 | 10.6 | 45.1 | 27 | 20 | 20 | 2 | 14 | 53 | 0 | 6 | 1 | 0 | 0 | 2 | 3 | 2.29 |
| RP | Thornburg, T.Thornburg, Tyler >> | 27 | 2016 | R | 66 | 26 | 0 | 1 | 0 | 2.16 | .254 | 0.93 | 5.2 | 3.3 | 13.4 | 33.1 | 19 | 9 | 8 | 4 | 12 | 49 | 0 | 5 | 0 | 0 | 0 | 3 | 0 | 2.97 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 52 | 23 | 0 | 1 | 1 | 3.26 | .278 | 1.12 | 7.5 | 2.7 | 10.2 | 30.1 | 25 | 11 | 11 | 4 | 9 | 34 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 3.47 |
| SP | Romero, R.Romero, Ricky >> | 26 | 2011 | L | 35 | 18 | 0 | 4 | 3 | 6.19 | .351 | 1.63 | 8.8 | 6.0 | 6.2 | 75.2 | 73 | 53 | 52 | 14 | 50 | 52 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.04 |