| SP | Verlander, J.Verlander, Justin † $$ >> | 36 | 2019 | R | 100 | 34 | 34 | 15 | 8 | 2.84 | .269 | 1.07 | 7.4 | 2.3 | 10.0 | 247.0 | 203 | 80 | 78 | 26 | 62 | 274 | 3 | 0 | 0 | 1 | 26 | 7 | 2 | 2.99 |
| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 35 | 35 | 18 | 14 | 3.80 | .272 | 1.09 | 8.3 | 1.5 | 9.4 | 258.1 | 239 | 112 | 109 | 36 | 43 | 270 | 9 | 0 | 0 | 3 | 20 | 8 | 7 | 3.31 |
| SP | Giolito, L.Giolito, Lucas † # $$ >> | 24 | 2019 | R | 72 | 33 | 33 | 20 | 11 | 3.68 | .281 | 1.12 | 7.2 | 2.8 | 9.3 | 210.1 | 169 | 88 | 86 | 26 | 66 | 217 | 4 | 0 | 0 | 2 | 18 | 12 | 4 | 3.66 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 26 | 2016 | R | 84 | 34 | 34 | 13 | 12 | 4.30 | .307 | 1.30 | 9.1 | 2.7 | 7.3 | 207.1 | 209 | 102 | 99 | 34 | 61 | 168 | 3 | 0 | 0 | 1 | 19 | 6 | 9 | 4.48 |
| SP | Keuchel, D.Keuchel, Dallas >> | 27 | 2015 | L | 69 | 31 | 31 | 10 | 11 | 5.35 | .326 | 1.44 | 10.3 | 2.7 | 7.0 | 198.1 | 227 | 122 | 118 | 29 | 59 | 153 | 4 | 0 | 0 | 1 | 13 | 2 | 3 | 4.28 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 98 | 81 | 0 | 7 | 6 | 3.10 | .265 | 1.04 | 6.8 | 2.6 | 10.8 | 107.1 | 81 | 38 | 37 | 16 | 31 | 128 | 0 | 11 | 6 | 0 | 0 | 4 | 0 | 3.53 |
| RP | Leclerc, J.Leclerc, Jose >> | 24 | 2018 | R | 89 | 60 | 0 | 3 | 2 | 2.78 | .324 | 1.39 | 6.2 | 6.5 | 10.4 | 64.2 | 44 | 21 | 20 | 4 | 46 | 74 | 0 | 10 | 0 | 0 | 0 | 3 | 2 | 3.80 |
| RP | Miller, A.Miller, Andrew >> | 30 | 2015 | L | 85 | 39 | 0 | 1 | 4 | 2.98 | .244 | 0.93 | 4.6 | 3.8 | 11.4 | 45.1 | 23 | 15 | 15 | 4 | 19 | 57 | 0 | 10 | 3 | 0 | 0 | 2 | 1 | 3.02 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 76 | 27 | 0 | 1 | 3 | 3.90 | .352 | 1.55 | 9.0 | 5.3 | 9.0 | 27.2 | 27 | 12 | 12 | 6 | 16 | 27 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 5.89 |
| SP | Lackey, J.Lackey, John >> | 38 | 2016 | R | 60 | 19 | 0 | 4 | 2 | 4.83 | .316 | 1.37 | 8.8 | 3.6 | 7.9 | 85.2 | 83 | 47 | 46 | 16 | 34 | 75 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 4.95 |