| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 19 | 19 | 8 | 3 | 3.51 | .274 | 1.12 | 7.3 | 2.8 | 9.6 | 128.1 | 104 | 50 | 50 | 22 | 40 | 136 | 1 | 0 | 0 | 0 | 12 | 1 | 0 | 4.07 |
| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 84 | 18 | 18 | 3 | 9 | 4.60 | .300 | 1.26 | 9.0 | 2.4 | 7.5 | 105.2 | 105 | 54 | 54 | 17 | 28 | 87 | 1 | 0 | 0 | 1 | 10 | 3 | 4 | 4.33 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 18 | 18 | 9 | 4 | 3.50 | .296 | 1.26 | 7.0 | 4.5 | 9.0 | 115.2 | 89 | 47 | 45 | 15 | 57 | 115 | 0 | 0 | 0 | 0 | 10 | 0 | 4 | 4.18 |
| SP | Beckett, J.Beckett, Josh >> | 31 | 2011 | R | 56 | 17 | 17 | 6 | 7 | 4.86 | .317 | 1.35 | 8.6 | 3.6 | 5.7 | 109.1 | 104 | 63 | 59 | 27 | 44 | 69 | 0 | 0 | 0 | 0 | 7 | 4 | 2 | 6.28 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 51 | 0 | 6 | 1 | 2.94 | .291 | 1.22 | 8.2 | 2.8 | 9.0 | 67.1 | 61 | 22 | 22 | 8 | 21 | 67 | 0 | 6 | 4 | 0 | 0 | 1 | 2 | 3.54 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 44 | 0 | 6 | 2 | 3.36 | .248 | 0.99 | 7.2 | 1.8 | 9.1 | 61.2 | 49 | 24 | 23 | 9 | 12 | 62 | 0 | 8 | 1 | 0 | 0 | 0 | 1 | 3.48 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 53 | 22 | 0 | 0 | 0 | 4.37 | .333 | 1.46 | 8.6 | 4.9 | 9.0 | 22.2 | 21 | 11 | 11 | 5 | 12 | 22 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 5.73 |