| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 95 | 27 | 27 | 14 | 8 | 3.02 | .273 | 1.08 | 7.1 | 2.7 | 8.2 | 179.0 | 141 | 61 | 60 | 19 | 53 | 164 | 4 | 0 | 0 | 1 | 21 | 8 | 6 | 3.57 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 26 | 26 | 11 | 6 | 3.91 | .299 | 1.25 | 8.5 | 2.8 | 6.2 | 135.2 | 128 | 62 | 59 | 23 | 42 | 93 | 0 | 0 | 0 | 0 | 7 | 4 | 3 | 4.86 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 26 | 26 | 11 | 9 | 4.11 | .295 | 1.24 | 7.8 | 3.4 | 8.1 | 160.0 | 139 | 75 | 73 | 22 | 60 | 144 | 3 | 0 | 0 | 0 | 14 | 2 | 6 | 4.15 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 25 | 25 | 2 | 9 | 6.34 | .337 | 1.49 | 10.2 | 3.3 | 6.4 | 127.2 | 144 | 92 | 90 | 27 | 46 | 91 | 2 | 0 | 0 | 0 | 7 | 5 | 4 | 5.54 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 25 | 24 | 7 | 11 | 6.01 | .347 | 1.56 | 11.3 | 2.8 | 5.8 | 139.1 | 175 | 96 | 93 | 30 | 43 | 90 | 1 | 0 | 0 | 0 | 8 | 4 | 2 | 5.53 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 56 | 0 | 3 | 8 | 3.36 | .258 | 1.03 | 6.6 | 2.7 | 11.0 | 67.0 | 49 | 25 | 25 | 9 | 20 | 82 | 0 | 28 | 4 | 0 | 0 | 1 | 2 | 3.24 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 46 | 0 | 4 | 0 | 2.04 | .226 | 0.87 | 6.4 | 1.5 | 8.9 | 66.1 | 47 | 15 | 15 | 6 | 11 | 65 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.71 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 43 | 0 | 4 | 1 | 3.21 | .296 | 1.20 | 7.5 | 3.4 | 11.9 | 47.2 | 39 | 17 | 17 | 6 | 18 | 62 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 3.36 |
| SP | Carlton, S.Carlton, Steve # >> | 28 | 1972 | L | 70 | 28 | 0 | 6 | 4 | 3.45 | .262 | 1.07 | 7.1 | 2.6 | 6.4 | 120.0 | 94 | 47 | 46 | 20 | 34 | 85 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.60 |