| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 19 | 19 | 8 | 8 | 2.99 | .278 | 1.15 | 7.5 | 2.9 | 5.3 | 141.2 | 118 | 51 | 47 | 18 | 45 | 83 | 1 | 0 | 0 | 0 | 13 | 1 | 3 | 4.46 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 77 | 18 | 18 | 8 | 6 | 4.69 | .310 | 1.34 | 8.9 | 3.2 | 6.3 | 121.0 | 119 | 64 | 63 | 14 | 43 | 85 | 4 | 0 | 0 | 0 | 8 | 1 | 7 | 4.19 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 19 | 18 | 10 | 3 | 3.71 | .292 | 1.22 | 7.6 | 3.4 | 6.9 | 114.0 | 96 | 52 | 47 | 16 | 43 | 88 | 1 | 0 | 1 | 0 | 9 | 2 | 3 | 4.46 |
| SP | Smoltz, J.Smoltz, John † # >> | 29 | 1996 | R | 62 | 18 | 17 | 11 | 5 | 2.58 | .242 | 0.95 | 6.3 | 2.3 | 9.3 | 122.0 | 85 | 38 | 35 | 17 | 31 | 126 | 2 | 0 | 0 | 1 | 13 | 1 | 3 | 3.53 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 94 | 44 | 0 | 2 | 5 | 3.67 | .290 | 1.18 | 6.8 | 4.0 | 8.8 | 41.2 | 31 | 17 | 17 | 6 | 18 | 40 | 0 | 27 | 3 | 0 | 0 | 2 | 0 | 4.41 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 35 | 0 | 0 | 0 | 4.50 | .292 | 1.24 | 7.9 | 3.2 | 9.5 | 34.0 | 30 | 17 | 17 | 8 | 12 | 36 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 43 | 0 | 2 | 1 | 4.00 | .315 | 1.36 | 9.4 | 2.8 | 8.4 | 45.0 | 47 | 20 | 20 | 7 | 14 | 42 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.16 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 32 | 0 | 3 | 2 | 3.19 | .304 | 1.31 | 8.0 | 4.0 | 10.0 | 36.2 | 32 | 13 | 13 | 2 | 16 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.83 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 14 | 0 | 1 | 0 | 2.30 | .319 | 1.40 | 6.6 | 6.6 | 10.2 | 15.2 | 11 | 4 | 4 | 0 | 11 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.93 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 18 | 0 | 1 | 2 | 4.30 | .313 | 1.33 | 7.4 | 4.7 | 7.4 | 29.1 | 24 | 14 | 14 | 4 | 15 | 24 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.79 |