| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 19 | 19 | 7 | 6 | 4.07 | .300 | 1.24 | 7.8 | 3.4 | 9.2 | 115.0 | 100 | 55 | 52 | 21 | 43 | 117 | 3 | 0 | 0 | 1 | 9 | 5 | 1 | 4.59 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 19 | 18 | 4 | 9 | 5.85 | .324 | 1.44 | 10.2 | 2.7 | 10.4 | 80.0 | 91 | 56 | 52 | 15 | 24 | 92 | 0 | 1 | 0 | 0 | 4 | 0 | 2 | 4.04 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 83 | 18 | 18 | 6 | 4 | 5.12 | .317 | 1.35 | 8.1 | 4.2 | 8.7 | 82.2 | 74 | 47 | 47 | 12 | 38 | 79 | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 4.48 |
| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 62 | 18 | 18 | 8 | 6 | 3.91 | .257 | 1.03 | 7.8 | 1.5 | 7.8 | 117.1 | 101 | 55 | 51 | 15 | 20 | 101 | 1 | 0 | 0 | 0 | 9 | 1 | 1 | 3.48 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 69 | 49 | 0 | 3 | 1 | 2.56 | .283 | 1.18 | 6.4 | 4.4 | 9.2 | 45.2 | 32 | 15 | 13 | 5 | 22 | 46 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 3.87 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 61 | 35 | 0 | 1 | 3 | 9.00 | .368 | 1.75 | 13.9 | 1.9 | 9.4 | 24.0 | 37 | 24 | 24 | 9 | 5 | 25 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 6.42 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 36 | 0 | 2 | 3 | 4.86 | .329 | 1.41 | 9.0 | 3.8 | 10.1 | 33.1 | 33 | 18 | 18 | 5 | 14 | 37 | 0 | 3 | 2 | 0 | 0 | 2 | 3 | 4.18 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 74 | 19 | 10 | 2 | 4 | 6.27 | .369 | 1.74 | 11.3 | 4.4 | 8.9 | 66.0 | 83 | 49 | 46 | 19 | 32 | 65 | 0 | 0 | 1 | 0 | 0 | 1 | 4 | 6.27 |