| SP | Hamels, C.Hamels, Cole >> | 27 | 2010 | L | 78 | 41 | 41 | 15 | 16 | 4.36 | .314 | 1.35 | 9.2 | 2.9 | 8.7 | 266.0 | 273 | 133 | 129 | 23 | 87 | 256 | 0 | 0 | 0 | 0 | 22 | 6 | 7 | 3.25 |
| SP | Lopez, M.Lopez, Marcelino >> | 22 | 1965 | L | 70 | 40 | 40 | 10 | 12 | 4.14 | .319 | 1.38 | 8.4 | 4.0 | 4.8 | 256.1 | 240 | 120 | 118 | 16 | 114 | 137 | 1 | 0 | 0 | 1 | 22 | 7 | 8 | 4.16 |
| SP | Jeffries, J.Jeffries, Jim >> | 29 | 1922 | L | 54 | 40 | 40 | 8 | 19 | 6.20 | .353 | 1.61 | 11.1 | 3.4 | 4.7 | 216.1 | 267 | 156 | 149 | 17 | 82 | 113 | 0 | 0 | 0 | 0 | 11 | 5 | 10 | 4.19 |
| SP | Billingsley, C.Billingsley, Chad >> | 28 | 2012 | R | 47 | 10 | 0 | 1 | 3 | 4.15 | .297 | 1.27 | 9.0 | 2.6 | 3.2 | 17.1 | 17 | 8 | 8 | 4 | 5 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.24 |
| RP | Spooneybarger, T.Spooneybarger, Tim >> | 24 | 2003 | R | 94 | 85 | 0 | 6 | 8 | 3.98 | .321 | 1.39 | 8.9 | 3.7 | 5.2 | 124.1 | 122 | 65 | 55 | 9 | 51 | 71 | 0 | 5 | 8 | 0 | 0 | 3 | 12 | 4.10 |
| RP | Caudill, B.Caudill, Bill † >> | 26 | 1982 | R | 87 | 79 | 0 | 7 | 3 | 2.92 | .288 | 1.21 | 7.1 | 3.9 | 8.7 | 104.2 | 82 | 34 | 34 | 6 | 45 | 100 | 0 | 12 | 1 | 0 | 0 | 0 | 2 | 3.13 |
| RP | Chouinard, B.Chouinard, Bobby >> | 27 | 1999 | R | 74 | 50 | 0 | 4 | 5 | 4.62 | .327 | 1.44 | 9.6 | 3.5 | 4.1 | 60.1 | 64 | 31 | 31 | 7 | 23 | 27 | 0 | 6 | 3 | 0 | 0 | 1 | 3 | 4.82 |