| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 28 | 28 | 14 | 7 | 3.94 | .290 | 1.20 | 7.9 | 2.9 | 7.7 | 212.2 | 186 | 94 | 93 | 18 | 69 | 181 | 4 | 0 | 0 | 1 | 13 | 5 | 3 | 3.44 |
| SP | Valenzuela, F.Valenzuela, Fernando >> | 26 | 1986 | L | 86 | 28 | 28 | 17 | 10 | 4.50 | .306 | 1.31 | 8.8 | 3.0 | 5.7 | 210.0 | 206 | 112 | 105 | 16 | 70 | 133 | 9 | 0 | 0 | 1 | 15 | 2 | 8 | 3.75 |
| SP | Drysdale, D.Drysdale, Don † >> | 28 | 1964 | R | 98 | 28 | 28 | 18 | 6 | 4.31 | .294 | 1.25 | 9.2 | 2.1 | 5.0 | 208.2 | 212 | 103 | 100 | 22 | 48 | 116 | 8 | 0 | 0 | 2 | 16 | 1 | 2 | 3.97 |
| SP | Pettitte, A.Pettitte, Andy † # >> | 31 | 2003 | L | 41 | 27 | 27 | 20 | 4 | 3.00 | .250 | 0.99 | 6.8 | 2.1 | 4.9 | 222.1 | 167 | 75 | 74 | 15 | 52 | 122 | 12 | 0 | 0 | 2 | 18 | 3 | 2 | 3.52 |
| RP | Hrabosky, A.Hrabosky, Al >> | 26 | 1975 | L | 82 | 29 | 0 | 0 | 1 | 1.26 | .271 | 1.12 | 6.4 | 3.9 | 7.1 | 14.1 | 10 | 4 | 2 | 1 | 6 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.64 |
| RP | Assenmacher, P.Assenmacher, Paul >> | 31 | 1991 | L | 77 | 7 | 0 | 1 | 2 | 9.00 | .444 | 2.40 | 16.2 | 5.4 | 9.0 | 5.0 | 9 | 5 | 5 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.80 |
| SP | Samardzija, J.Samardzija, Jeff >> | 34 | 2019 | R | 89 | 9 | 0 | 0 | 0 | 6.00 | .345 | 1.56 | 11.3 | 2.8 | 4.3 | 36.0 | 45 | 25 | 24 | 4 | 11 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.50 |