| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 100 | 16 | 16 | 9 | 4 | 3.37 | .255 | 1.02 | 7.1 | 2.2 | 9.8 | 117.2 | 92 | 45 | 44 | 16 | 28 | 127 | 4 | 0 | 0 | 1 | 11 | 1 | 1 | 3.35 |
| SP | Vazquez, J.Vazquez, Javier >> | 33 | 2009 | R | 87 | 15 | 15 | 5 | 3 | 6.02 | .353 | 1.61 | 11.0 | 3.7 | 9.7 | 83.2 | 101 | 56 | 56 | 12 | 34 | 89 | 0 | 0 | 0 | 0 | 5 | 2 | 4 | 4.04 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 15 | 15 | 1 | 2 | 5.22 | .338 | 1.45 | 9.6 | 3.6 | 7.1 | 58.2 | 62 | 34 | 34 | 10 | 23 | 46 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 5.10 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 17 | 15 | 5 | 6 | 5.96 | .334 | 1.51 | 10.2 | 3.5 | 6.6 | 93.2 | 105 | 63 | 62 | 23 | 36 | 68 | 0 | 1 | 1 | 0 | 5 | 0 | 0 | 5.91 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 40 | 0 | 5 | 2 | 3.67 | .290 | 1.19 | 8.7 | 2.1 | 10.0 | 56.1 | 54 | 23 | 23 | 6 | 13 | 62 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 2.98 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 97 | 32 | 0 | 2 | 3 | 3.00 | .258 | 1.02 | 5.8 | 3.4 | 9.0 | 48.0 | 31 | 16 | 16 | 1 | 18 | 48 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 2.46 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 90 | 34 | 0 | 4 | 5 | 4.95 | .276 | 1.15 | 6.1 | 4.4 | 7.7 | 43.2 | 29 | 25 | 24 | 8 | 21 | 37 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 5.16 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 25 | 0 | 3 | 3 | 2.91 | .346 | 1.59 | 11.1 | 3.2 | 8.5 | 34.0 | 42 | 12 | 11 | 3 | 12 | 32 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.32 |
| RP | Politte, C.Politte, Cliff >> | 31 | 2005 | R | 67 | 24 | 0 | 0 | 2 | 3.51 | .319 | 1.32 | 6.8 | 5.4 | 6.1 | 25.2 | 19 | 10 | 10 | 3 | 15 | 17 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 5.24 |
| RP | Isringhausen, J.Isringhausen, Jason >> | 32 | 2004 | R | 41 | 20 | 0 | 1 | 2 | 6.00 | .321 | 1.42 | 10.1 | 2.6 | 4.5 | 24.0 | 27 | 16 | 16 | 4 | 7 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.04 |