| SP | Sheets, B.Sheets, Ben # >> | 26 | 2004 | R | 91 | 25 | 25 | 10 | 7 | 3.91 | .272 | 1.11 | 8.3 | 1.7 | 9.1 | 156.2 | 144 | 70 | 68 | 21 | 30 | 158 | 2 | 0 | 0 | 2 | 14 | 2 | 2 | 3.34 |
| SP | Wakefield, T.Wakefield, Tim >> | 36 | 2002 | R | 84 | 24 | 24 | 5 | 7 | 3.31 | .301 | 1.25 | 8.8 | 2.5 | 6.6 | 100.2 | 98 | 39 | 37 | 9 | 28 | 73 | 1 | 0 | 0 | 1 | 1 | 4 | 2 | 3.67 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 24 | 24 | 11 | 4 | 4.12 | .324 | 1.43 | 8.6 | 4.3 | 6.6 | 135.1 | 129 | 66 | 62 | 15 | 64 | 99 | 0 | 0 | 0 | 0 | 13 | 2 | 3 | 4.44 |
| SP | Prior, M.Prior, Mark # >> | 23 | 2003 | R | 69 | 25 | 24 | 7 | 8 | 6.21 | .332 | 1.43 | 10.2 | 2.7 | 10.2 | 137.2 | 156 | 99 | 95 | 27 | 41 | 156 | 2 | 0 | 0 | 0 | 8 | 8 | 8 | 4.36 |
| SP | Nolasco, R.Nolasco, Ricky >> | 26 | 2008 | R | 56 | 25 | 22 | 11 | 8 | 4.39 | .324 | 1.39 | 9.8 | 2.7 | 6.3 | 135.1 | 147 | 69 | 66 | 21 | 41 | 94 | 0 | 0 | 1 | 0 | 12 | 7 | 2 | 4.70 |
| RP | Saito, T.Saito, Takashi † >> | 37 | 2007 | R | 100 | 68 | 0 | 5 | 3 | 2.63 | .288 | 1.16 | 6.5 | 3.9 | 9.2 | 89.0 | 64 | 31 | 26 | 9 | 39 | 91 | 0 | 4 | 2 | 0 | 0 | 5 | 0 | 3.75 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 70 | 0 | 5 | 5 | 4.87 | .292 | 1.21 | 8.4 | 2.5 | 7.3 | 85.0 | 79 | 46 | 46 | 9 | 24 | 69 | 0 | 11 | 1 | 0 | 0 | 2 | 1 | 3.67 |
| RP | Mota, G.Mota, Guillermo >> | 30 | 2003 | R | 51 | 50 | 0 | 0 | 3 | 3.60 | .321 | 1.38 | 9.5 | 3.0 | 7.1 | 60.0 | 63 | 24 | 24 | 9 | 20 | 47 | 0 | 4 | 5 | 0 | 0 | 2 | 0 | 4.48 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 39 | 0 | 0 | 3 | 2.98 | .295 | 1.21 | 6.8 | 4.2 | 5.0 | 45.1 | 34 | 17 | 15 | 2 | 21 | 25 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 4.00 |
| RP | Aardsma, D.Aardsma, David >> | 28 | 2009 | R | 36 | 29 | 0 | 3 | 1 | 3.86 | .287 | 1.13 | 6.9 | 3.5 | 11.8 | 39.2 | 30 | 17 | 17 | 4 | 15 | 51 | 0 | 2 | 3 | 0 | 0 | 3 | 0 | 3.10 |