| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 98 | 13 | 13 | 2 | 5 | 3.75 | .308 | 1.28 | 8.8 | 2.8 | 8.5 | 57.2 | 56 | 24 | 24 | 7 | 18 | 54 | 0 | 0 | 0 | 0 | 1 | 3 | 6 | 3.81 |
| SP | Hernandez, F.Hernandez, Felix >> | 19 | 2005 | R | 96 | 13 | 13 | 5 | 4 | 4.89 | .335 | 1.46 | 10.2 | 3.0 | 6.4 | 77.1 | 87 | 42 | 42 | 20 | 26 | 55 | 2 | 0 | 0 | 0 | 7 | 4 | 0 | 6.12 |
| SP | Loaiza, E.Loaiza, Esteban # >> | 32 | 2003 | R | 59 | 13 | 13 | 3 | 2 | 5.24 | .335 | 1.50 | 10.3 | 3.3 | 7.4 | 68.2 | 78 | 43 | 40 | 14 | 25 | 56 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 5.18 |
| SP | Maddux, G.Maddux, Greg >> | 34 | 2000 | R | 57 | 13 | 13 | 5 | 4 | 6.78 | .381 | 1.85 | 13.6 | 3.0 | 6.1 | 65.0 | 98 | 49 | 49 | 12 | 22 | 44 | 0 | 0 | 0 | 0 | 3 | 0 | 2 | 5.06 |
| SP | Burkett, J.Burkett, John >> | 37 | 2001 | R | 50 | 12 | 12 | 6 | 4 | 4.66 | .323 | 1.43 | 8.9 | 4.1 | 8.0 | 63.2 | 62 | 33 | 33 | 11 | 29 | 56 | 0 | 0 | 0 | 0 | 5 | 0 | 2 | 4.87 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 91 | 37 | 0 | 1 | 6 | 8.14 | .367 | 1.69 | 10.3 | 4.9 | 5.8 | 42.0 | 48 | 38 | 38 | 11 | 23 | 27 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 6.90 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 44 | 0 | 2 | 3 | 5.71 | .316 | 1.33 | 10.6 | 1.6 | 9.8 | 34.2 | 40 | 23 | 22 | 8 | 6 | 37 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 4.59 |
| RP | Sasaki, K.Sasaki, Kazuhiro >> | 33 | 2001 | R | 63 | 35 | 0 | 2 | 0 | 2.76 | .291 | 1.20 | 7.5 | 3.4 | 7.3 | 42.1 | 35 | 14 | 13 | 3 | 16 | 34 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.52 |
| RP | Cordero, C.Cordero, Chad >> | 23 | 2005 | R | 49 | 29 | 0 | 1 | 1 | 3.73 | .314 | 1.34 | 8.7 | 3.5 | 5.2 | 31.1 | 30 | 13 | 13 | 5 | 12 | 18 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.19 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 35 | 20 | 0 | 2 | 0 | 3.16 | .267 | 1.05 | 5.8 | 4.0 | 10.8 | 25.2 | 16 | 9 | 9 | 5 | 11 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.64 |
| SP | Appier, K.Appier, Kevin >> | 34 | 2001 | R | 37 | 11 | 0 | 1 | 1 | 5.14 | .364 | 1.71 | 13.5 | 1.9 | 7.1 | 14.0 | 21 | 8 | 8 | 2 | 3 | 11 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.93 |