| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 34 | 34 | 9 | 10 | 4.07 | .307 | 1.31 | 7.0 | 4.8 | 10.1 | 177.0 | 138 | 81 | 80 | 18 | 94 | 198 | 0 | 0 | 0 | 0 | 12 | 3 | 3 | 3.73 |
| SP | Wakefield, T.Wakefield, Tim # >> | 36 | 2002 | R | 84 | 32 | 32 | 1 | 9 | 4.85 | .322 | 1.37 | 9.0 | 3.3 | 7.8 | 117.0 | 117 | 69 | 63 | 22 | 43 | 102 | 0 | 0 | 0 | 0 | 0 | 7 | 3 | 4.98 |
| SP | Buehrle, M.Buehrle, Mark >> | 22 | 2001 | L | 68 | 33 | 32 | 9 | 12 | 5.50 | .329 | 1.44 | 9.9 | 3.1 | 6.7 | 160.1 | 176 | 101 | 98 | 34 | 55 | 119 | 0 | 0 | 0 | 0 | 12 | 5 | 2 | 5.40 |
| SP | Garcia, F.Garcia, Freddy # >> | 26 | 2001 | R | 62 | 32 | 28 | 10 | 9 | 4.94 | .331 | 1.45 | 9.7 | 3.4 | 7.2 | 182.1 | 196 | 107 | 100 | 37 | 69 | 146 | 2 | 0 | 0 | 0 | 14 | 6 | 4 | 5.27 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 85 | 0 | 7 | 9 | 3.47 | .303 | 1.30 | 8.4 | 3.3 | 9.4 | 114.0 | 106 | 47 | 44 | 28 | 42 | 119 | 0 | 3 | 4 | 0 | 0 | 1 | 0 | 5.24 |
| RP | Springer, R.Springer, Russ >> | 39 | 2007 | R | 78 | 76 | 0 | 7 | 4 | 3.01 | .302 | 1.28 | 7.5 | 4.1 | 7.8 | 95.2 | 79 | 34 | 32 | 6 | 43 | 82 | 0 | 5 | 3 | 0 | 0 | 2 | 1 | 3.52 |
| RP | Wheeler, D.Wheeler, Dan >> | 32 | 2009 | R | 67 | 66 | 0 | 4 | 5 | 2.82 | .229 | 0.88 | 6.7 | 1.2 | 6.1 | 83.0 | 62 | 27 | 26 | 6 | 11 | 56 | 0 | 7 | 3 | 0 | 0 | 1 | 5 | 3.02 |
| RP | Thornton, M.Thornton, Matt >> | 32 | 2008 | L | 54 | 96 | 0 | 4 | 5 | 4.03 | .322 | 1.39 | 8.9 | 3.6 | 8.0 | 87.0 | 86 | 40 | 39 | 13 | 35 | 77 | 0 | 2 | 1 | 0 | 0 | 3 | 6 | 4.48 |
| RP | Kim, B.Kim, Byung-Hyun >> | 23 | 2002 | R | 37 | 66 | 0 | 2 | 4 | 6.44 | .339 | 1.49 | 9.3 | 4.3 | 8.6 | 65.2 | 67 | 50 | 47 | 13 | 31 | 62 | 0 | 6 | 1 | 0 | 0 | 3 | 0 | 5.26 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 41 | 31 | 3 | 2 | 3 | 7.40 | .392 | 1.87 | 10.5 | 6.6 | 9.0 | 48.2 | 56 | 41 | 40 | 14 | 35 | 48 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 7.17 |