| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 16 | 16 | 3 | 10 | 6.78 | .355 | 1.61 | 10.5 | 4.1 | 8.8 | 83.2 | 97 | 69 | 63 | 18 | 38 | 81 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 5.35 |
| SP | Maddux, G.Maddux, Greg # >> | 34 | 2000 | R | 58 | 15 | 15 | 4 | 8 | 7.11 | .375 | 1.75 | 13.0 | 2.7 | 6.8 | 76.0 | 110 | 73 | 60 | 13 | 23 | 57 | 1 | 0 | 0 | 0 | 3 | 4 | 1 | 4.79 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 68 | 47 | 0 | 0 | 1 | 3.49 | .279 | 1.14 | 7.9 | 2.4 | 9.9 | 49.0 | 43 | 19 | 19 | 5 | 13 | 54 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 2.98 |
| RP | Guardado, E.Guardado, Eddie >> | 34 | 2004 | L | 56 | 44 | 0 | 1 | 1 | 5.23 | .347 | 1.52 | 7.2 | 6.6 | 8.6 | 41.1 | 33 | 25 | 24 | 7 | 30 | 39 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 5.73 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 60 | 39 | 0 | 0 | 1 | 4.35 | .320 | 1.37 | 9.6 | 2.9 | 9.9 | 49.2 | 52 | 24 | 24 | 6 | 16 | 54 | 0 | 1 | 1 | 0 | 0 | 2 | 1 | 3.49 |
| SU | Perez, R.Perez, Rafael >> | 25 | 2007 | L | 65 | 39 | 0 | 0 | 3 | 4.10 | .309 | 1.34 | 8.1 | 4.2 | 10.5 | 41.2 | 37 | 21 | 19 | 5 | 19 | 48 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 3.63 |
| CL | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 96 | 38 | 0 | 2 | 6 | 4.97 | .302 | 1.30 | 9.9 | 2.0 | 7.2 | 41.2 | 45 | 23 | 23 | 7 | 9 | 33 | 0 | 15 | 2 | 0 | 0 | 0 | 1 | 4.27 |
| SP | Willis, D.Willis, Dontrelle >> | 23 | 2005 | L | 49 | 19 | 0 | 2 | 2 | 7.26 | .341 | 1.53 | 11.8 | 2.1 | 5.4 | 48.1 | 63 | 40 | 39 | 14 | 11 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.33 |