| SP | Johnson, R.Johnson, Randy >> | 38 | 2001 | L | 97 | 15 | 15 | 6 | 4 | 3.93 | .306 | 1.29 | 8.8 | 2.9 | 10.1 | 100.2 | 98 | 44 | 44 | 13 | 32 | 112 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 3.50 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 86 | 15 | 15 | 5 | 5 | 4.29 | .304 | 1.31 | 9.2 | 2.7 | 6.4 | 98.2 | 100 | 48 | 47 | 9 | 29 | 70 | 4 | 0 | 0 | 1 | 7 | 0 | 3 | 3.65 |
| SP | Duchscherer, J.Duchscherer, Justin >> | 31 | 2008 | R | 85 | 15 | 15 | 4 | 6 | 4.81 | .307 | 1.26 | 8.7 | 2.7 | 5.6 | 88.0 | 85 | 48 | 47 | 16 | 26 | 55 | 0 | 0 | 0 | 0 | 7 | 6 | 3 | 5.20 |
| SP | Alvarez, W.Alvarez, Wilson >> | 33 | 2003 | L | 73 | 14 | 14 | 3 | 5 | 5.01 | .328 | 1.47 | 9.0 | 4.3 | 6.9 | 59.1 | 59 | 37 | 33 | 5 | 28 | 45 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.00 |
| SP | Verlander, J.Verlander, Justin # >> | 26 | 2009 | R | 43 | 14 | 14 | 5 | 5 | 5.29 | .305 | 1.31 | 9.5 | 2.4 | 7.3 | 78.1 | 82 | 48 | 46 | 12 | 21 | 63 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 4.19 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 28 | 0 | 2 | 2 | 4.78 | .338 | 1.38 | 9.3 | 3.1 | 8.4 | 32.0 | 33 | 18 | 17 | 6 | 11 | 30 | 0 | 3 | 2 | 0 | 0 | 5 | 1 | 5.06 |
| RP | Mantei, M.Mantei, Matt >> | 30 | 2003 | R | 59 | 25 | 0 | 3 | 0 | 4.31 | .282 | 1.18 | 7.8 | 2.9 | 9.6 | 31.1 | 27 | 15 | 15 | 5 | 10 | 33 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.94 |
| SP | Kazmir, S.Kazmir, Scott >> | 24 | 2008 | L | 40 | 9 | 0 | 0 | 0 | 0.60 | .308 | 1.27 | 5.4 | 6.0 | 9.6 | 15.0 | 9 | 3 | 1 | 0 | 10 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.07 |
| RP | Otsuka, A.Otsuka, Akinori >> | 32 | 2004 | R | 42 | 19 | 0 | 0 | 0 | 3.32 | .198 | 0.74 | 4.7 | 2.1 | 11.1 | 21.2 | 11 | 8 | 8 | 3 | 5 | 26 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.10 |