| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 100 | 34 | 34 | 10 | 17 | 4.51 | .315 | 1.35 | 8.8 | 3.4 | 9.8 | 215.1 | 210 | 109 | 108 | 29 | 81 | 233 | 2 | 0 | 0 | 1 | 19 | 6 | 5 | 3.80 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 93 | 33 | 33 | 11 | 16 | 4.17 | .295 | 1.24 | 8.8 | 2.3 | 9.8 | 226.2 | 221 | 112 | 105 | 28 | 59 | 245 | 5 | 0 | 0 | 1 | 18 | 4 | 4 | 3.28 |
| SP | Weaver, J.Weaver, Jered >> | 24 | 2006 | R | 83 | 32 | 32 | 10 | 9 | 3.91 | .293 | 1.20 | 7.7 | 3.2 | 6.8 | 200.1 | 170 | 89 | 87 | 28 | 70 | 152 | 0 | 0 | 0 | 0 | 18 | 9 | 3 | 4.49 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 61 | 31 | 31 | 10 | 18 | 4.92 | .317 | 1.36 | 9.0 | 3.3 | 7.3 | 201.1 | 200 | 114 | 110 | 34 | 74 | 164 | 3 | 0 | 0 | 0 | 13 | 6 | 3 | 4.76 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 61 | 0 | 6 | 6 | 2.41 | .243 | 0.92 | 6.6 | 1.7 | 11.0 | 67.1 | 49 | 18 | 18 | 3 | 13 | 82 | 0 | 35 | 5 | 0 | 0 | 3 | 0 | 1.85 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 97 | 0 | 3 | 3 | 2.79 | .272 | 1.09 | 6.5 | 3.4 | 9.4 | 103.1 | 74 | 34 | 32 | 10 | 39 | 108 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 3.39 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 83 | 87 | 0 | 2 | 1 | 3.11 | .284 | 1.16 | 8.0 | 2.5 | 9.4 | 72.1 | 64 | 30 | 25 | 6 | 20 | 75 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 2.92 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 60 | 0 | 1 | 1 | 2.90 | .320 | 1.34 | 9.5 | 2.7 | 10.6 | 40.1 | 42 | 18 | 13 | 4 | 12 | 47 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 3.08 |
| RP | Street, H.Street, Huston >> | 24 | 2007 | R | 68 | 74 | 0 | 3 | 3 | 3.24 | .277 | 1.15 | 7.1 | 3.3 | 9.6 | 58.1 | 46 | 21 | 21 | 7 | 21 | 62 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.52 |
| RP | Masset, N.Masset, Nick >> | 27 | 2009 | R | 46 | 49 | 0 | 2 | 0 | 4.15 | .331 | 1.49 | 8.8 | 4.6 | 7.6 | 39.0 | 38 | 19 | 18 | 4 | 20 | 33 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.18 |
| RP | Linebrink, S.Linebrink, Scott >> | 28 | 2004 | R | 45 | 33 | 0 | 2 | 1 | 3.48 | .291 | 1.23 | 8.1 | 3.1 | 6.4 | 41.1 | 37 | 17 | 16 | 6 | 14 | 29 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.51 |