| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 88 | 20 | 20 | 6 | 4 | 3.72 | .267 | 1.09 | 6.9 | 2.9 | 9.9 | 118.2 | 91 | 50 | 49 | 10 | 38 | 130 | 3 | 0 | 0 | 0 | 10 | 1 | 0 | 2.89 |
| SP | Greinke, Z.Greinke, Zack >> | 36 | 2019 | R | 70 | 20 | 20 | 6 | 9 | 5.40 | .323 | 1.40 | 9.7 | 3.0 | 5.8 | 108.1 | 116 | 70 | 65 | 14 | 36 | 70 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 4.47 |
| SP | Kelly, M.Kelly, Merrill # >> | 36 | 2025 | R | 46 | 19 | 19 | 5 | 6 | 6.55 | .340 | 1.51 | 10.6 | 3.0 | 7.3 | 89.1 | 105 | 66 | 65 | 16 | 30 | 72 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 4.83 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 73 | 55 | 0 | 5 | 2 | 4.27 | .307 | 1.29 | 7.1 | 4.6 | 7.5 | 65.1 | 51 | 33 | 31 | 4 | 33 | 54 | 0 | 2 | 2 | 0 | 0 | 3 | 3 | 3.80 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 68 | 51 | 0 | 5 | 3 | 2.87 | .342 | 1.52 | 7.1 | 6.6 | 10.4 | 53.1 | 42 | 17 | 17 | 5 | 39 | 61 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 4.25 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 49 | 40 | 0 | 3 | 2 | 4.60 | .352 | 1.60 | 9.0 | 5.4 | 7.5 | 43.0 | 43 | 22 | 22 | 2 | 26 | 36 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 3.81 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 46 | 30 | 0 | 1 | 0 | 4.75 | .359 | 1.65 | 9.9 | 5.1 | 8.7 | 30.1 | 33 | 16 | 16 | 4 | 17 | 29 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 4.60 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 33 | 24 | 0 | 1 | 4 | 8.51 | .366 | 1.73 | 12.6 | 3.3 | 4.5 | 30.2 | 42 | 29 | 29 | 5 | 11 | 15 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 5.27 |
| RP | Nelson, K.Nelson, Kyle >> | 25 | 2022 | L | 23 | 73 | 0 | 1 | 3 | 6.70 | .376 | 1.76 | 10.4 | 5.5 | 7.2 | 44.1 | 51 | 34 | 33 | 8 | 27 | 35 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 5.75 |