| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 79 | 20 | 20 | 5 | 11 | 6.01 | .339 | 1.53 | 9.9 | 3.9 | 9.1 | 112.1 | 123 | 84 | 75 | 17 | 49 | 113 | 0 | 0 | 0 | 0 | 6 | 1 | 2 | 4.29 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 91 | 20 | 20 | 9 | 9 | 3.97 | .308 | 1.31 | 8.9 | 2.9 | 9.7 | 122.1 | 121 | 57 | 54 | 12 | 39 | 132 | 0 | 0 | 0 | 0 | 10 | 3 | 0 | 3.15 |
| SP | Lolich, M.Lolich, Mickey # >> | 27 | 1967 | L | 39 | 20 | 20 | 7 | 6 | 5.24 | .320 | 1.39 | 8.9 | 3.7 | 6.7 | 122.0 | 120 | 76 | 71 | 17 | 50 | 91 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 4.60 |
| SP | Fryman, W.Fryman, Woodie >> | 32 | 1972 | L | 30 | 19 | 19 | 4 | 13 | 6.84 | .349 | 1.59 | 10.7 | 3.6 | 5.4 | 100.0 | 119 | 82 | 76 | 19 | 40 | 60 | 2 | 0 | 0 | 0 | 6 | 2 | 3 | 5.53 |
| SP | Wilson, E.Wilson, Earl >> | 34 | 1968 | R | 28 | 10 | 10 | 1 | 7 | 8.14 | .349 | 1.59 | 11.4 | 3.0 | 4.6 | 45.1 | 57 | 42 | 41 | 6 | 15 | 23 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 4.78 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 42 | 47 | 0 | 3 | 1 | 5.59 | .358 | 1.64 | 11.4 | 3.3 | 6.9 | 74.0 | 94 | 49 | 46 | 16 | 27 | 57 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 5.49 |
| SU | Melton, T.Melton, Troy >> | 24 | 2025 | R | 26 | 26 | 0 | 0 | 0 | 4.50 | .333 | 1.47 | 8.1 | 5.1 | 3.6 | 30.0 | 27 | 15 | 15 | 5 | 17 | 12 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 6.17 |
| CL | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 67 | 33 | 0 | 0 | 7 | 4.89 | .340 | 1.49 | 8.0 | 5.4 | 6.9 | 35.0 | 31 | 22 | 19 | 4 | 21 | 27 | 0 | 20 | 4 | 0 | 0 | 2 | 2 | 4.91 |
| RP | Alcantara, V.Alcantara, Victor >> | 25 | 2018 | R | 18 | 36 | 0 | 0 | 0 | 4.14 | .287 | 1.21 | 9.7 | 1.3 | 5.5 | 41.1 | 44 | 22 | 19 | 5 | 6 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.80 |
| RP | Jimenez, J.Jimenez, Joe >> | 27 | 2022 | R | 20 | 32 | 0 | 2 | 1 | 3.41 | .260 | 1.03 | 7.1 | 2.2 | 9.0 | 37.0 | 29 | 22 | 14 | 5 | 9 | 37 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.57 |
| RP | Lasher, F.Lasher, Fred >> | 26 | 1967 | R | 15 | 22 | 0 | 0 | 0 | 5.97 | .348 | 1.60 | 10.6 | 4.2 | 7.4 | 28.2 | 33 | 19 | 19 | 6 | 13 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.54 |