| SP | Sparks, T.Sparks, Tully >> | 32 | 1906 | R | 67 | 13 | 13 | 4 | 3 | 4.32 | .317 | 1.38 | 9.5 | 2.9 | 3.7 | 83.1 | 88 | 47 | 40 | 13 | 27 | 34 | 2 | 0 | 0 | 0 | 7 | 1 | 0 | 5.23 |
| SP | Schilling, C.Schilling, Curt >> | 26 | 1992 | R | 72 | 13 | 13 | 5 | 3 | 4.21 | .335 | 1.49 | 10.3 | 3.3 | 5.0 | 72.2 | 82 | 41 | 34 | 9 | 26 | 40 | 0 | 0 | 0 | 0 | 3 | 2 | 1 | 4.68 |
| SP | Sanders, B.Sanders, Ben # >> | 23 | 1888 | R | 47 | 13 | 13 | 9 | 3 | 3.67 | .283 | 1.17 | 8.7 | 1.9 | 5.5 | 95.2 | 92 | 42 | 39 | 8 | 20 | 58 | 5 | 0 | 0 | 1 | 6 | 1 | 3 | 3.54 |
| SP | Christenson, L.Christenson, Larry >> | 25 | 1978 | R | 36 | 12 | 12 | 7 | 3 | 3.24 | .301 | 1.25 | 8.2 | 3.0 | 4.8 | 89.0 | 81 | 46 | 32 | 11 | 30 | 47 | 0 | 0 | 0 | 0 | 8 | 4 | 1 | 4.70 |
| SU | Bastardo, A.Bastardo, Antonio >> | 26 | 2011 | L | 74 | 18 | 0 | 0 | 0 | 1.42 | .260 | 1.05 | 5.7 | 3.8 | 9.0 | 19.0 | 12 | 4 | 3 | 1 | 8 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.95 |
| RP | Wagner, B.Wagner, Billy >> | 33 | 2004 | L | 83 | 31 | 0 | 1 | 0 | 2.97 | .315 | 1.35 | 9.3 | 3.0 | 8.2 | 33.1 | 34 | 14 | 11 | 3 | 11 | 30 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.45 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 35 | 2015 | R | 44 | 21 | 0 | 0 | 2 | 5.64 | .374 | 1.75 | 10.6 | 5.3 | 9.4 | 22.1 | 26 | 14 | 14 | 2 | 13 | 23 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Hoffman, J.Hoffman, Jeff >> | 30 | 2023 | R | 71 | 13 | 0 | 3 | 1 | 5.29 | .363 | 1.71 | 10.1 | 5.3 | 4.8 | 17.0 | 19 | 11 | 10 | 3 | 10 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |
| RP | De Fratus, J.De Fratus, Justin >> | 26 | 2014 | R | 36 | 10 | 0 | 1 | 2 | 3.00 | .265 | 1.08 | 6.8 | 3.0 | 6.8 | 12.0 | 9 | 5 | 4 | 2 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.67 |
| RP | Schrenk, S.Schrenk, Steve >> | 31 | 1999 | R | 33 | 18 | 0 | 0 | 0 | 3.09 | .255 | 0.99 | 7.8 | 1.2 | 5.1 | 23.1 | 20 | 11 | 8 | 1 | 3 | 13 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.96 |