| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 92 | 5 | 5 | 2 | 2 | 3.27 | .313 | 1.33 | 9.3 | 2.7 | 10.1 | 33.0 | 34 | 14 | 12 | 5 | 10 | 37 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 3.73 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 83 | 5 | 5 | 1 | 3 | 3.60 | .331 | 1.49 | 10.5 | 2.8 | 8.2 | 35.0 | 41 | 14 | 14 | 4 | 11 | 32 | 1 | 0 | 0 | 1 | 3 | 0 | 1 | 3.60 |
| SP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 89 | 5 | 5 | 0 | 0 | 0.00 | .228 | 0.89 | 5.8 | 2.6 | 3.9 | 14.2 | 9 | 0 | 0 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 77 | 4 | 4 | 2 | 1 | 2.92 | .288 | 1.18 | 9.8 | 1.1 | 10.1 | 24.2 | 26 | 8 | 8 | 1 | 3 | 27 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 1.79 |
| SP | Robinson, J.Robinson, Jeff >> | 27 | 1988 | R | 65 | 4 | 4 | 2 | 1 | 6.17 | .397 | 1.93 | 11.3 | 6.3 | 8.2 | 23.1 | 29 | 17 | 16 | 3 | 16 | 21 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.09 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 83 | 9 | 0 | 1 | 1 | 3.86 | .314 | 1.37 | 10.6 | 2.5 | 13.1 | 11.2 | 13 | 5 | 5 | 2 | 3 | 16 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.27 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 72 | 10 | 0 | 0 | 2 | 6.00 | .345 | 1.58 | 9.8 | 4.5 | 6.8 | 12.0 | 13 | 8 | 8 | 1 | 6 | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.08 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 56 | 3 | 0 | 0 | 0 | 10.13 | .429 | 2.25 | 18.0 | 9.0 | 22.5 | 2.2 | 4 | 3 | 3 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.00 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 66 | 5 | 0 | 0 | 0 | 8.31 | .381 | 1.85 | 11.3 | 6.8 | 9.0 | 4.1 | 5 | 4 | 4 | 1 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.50 |
| RP | Walker, J.Walker, Jamie >> | 31 | 2002 | L | 49 | 7 | 0 | 0 | 0 | 2.70 | .310 | 1.35 | 9.0 | 4.5 | 10.5 | 6.2 | 6 | 2 | 2 | 0 | 3 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.17 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 48 | 5 | 0 | 0 | 1 | 12.46 | .480 | 2.77 | 20.3 | 6.8 | 2.3 | 4.1 | 9 | 6 | 6 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.75 |
| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 60 | 6 | 0 | 4 | 0 | 0.84 | .198 | 0.74 | 4.5 | 2.3 | 5.6 | 32.1 | 16 | 6 | 3 | 1 | 8 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.91 |