| SP | Koufax, S.Koufax, Sandy >> | 31 | 1965 | L | 82 | 31 | 31 | 9 | 18 | 5.33 | .328 | 1.44 | 9.9 | 3.1 | 7.5 | 221.0 | 242 | 133 | 131 | 26 | 77 | 185 | 7 | 0 | 0 | 1 | 12 | 5 | 8 | 3.97 |
| SP | Alexander, P.Alexander, Pete >> | 29 | 1915 | R | 81 | 30 | 30 | 10 | 10 | 4.63 | .310 | 1.31 | 8.6 | 3.2 | 5.0 | 217.2 | 208 | 117 | 112 | 36 | 78 | 121 | 9 | 0 | 0 | 2 | 14 | 8 | 1 | 5.23 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1908 | R | 66 | 28 | 27 | 10 | 11 | 5.21 | .340 | 1.54 | 10.4 | 3.4 | 4.5 | 190.0 | 220 | 122 | 110 | 15 | 72 | 94 | 4 | 0 | 0 | 0 | 13 | 2 | 2 | 4.21 |
| SP | Pfiester, J.Pfiester, Jack >> | 29 | 1906 | L | 50 | 27 | 27 | 10 | 11 | 5.18 | .336 | 1.50 | 9.6 | 3.9 | 4.5 | 196.1 | 209 | 121 | 113 | 28 | 85 | 97 | 10 | 0 | 0 | 0 | 12 | 4 | 5 | 5.23 |
| SP | Gooden, D.Gooden, Dwight >> | 22 | 1985 | R | 60 | 20 | 17 | 6 | 10 | 6.63 | .362 | 1.68 | 11.1 | 4.1 | 5.7 | 114.0 | 140 | 85 | 84 | 16 | 52 | 72 | 1 | 0 | 0 | 0 | 5 | 2 | 4 | 4.98 |
| RP | Street, H.Street, Huston >> | 30 | 2012 | R | 71 | 72 | 0 | 4 | 2 | 4.16 | .322 | 1.38 | 8.6 | 3.8 | 7.4 | 80.0 | 76 | 37 | 37 | 7 | 34 | 66 | 0 | 9 | 2 | 0 | 0 | 4 | 0 | 3.91 |
| RP | Chapman, A.Chapman, Aroldis >> | 25 | 2012 | L | 95 | 50 | 0 | 6 | 4 | 2.58 | .287 | 1.18 | 6.5 | 4.1 | 9.4 | 66.1 | 48 | 20 | 19 | 5 | 30 | 69 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 3.35 |
| RP | Hoffman, T.Hoffman, Trevor >> | 32 | 1998 | R | 37 | 24 | 0 | 0 | 3 | 7.20 | .355 | 1.65 | 9.5 | 5.4 | 5.9 | 20.0 | 21 | 16 | 16 | 5 | 12 | 13 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 6.75 |