| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 91 | 35 | 35 | 14 | 12 | 3.93 | .305 | 1.32 | 9.7 | 2.2 | 5.8 | 249.2 | 267 | 120 | 109 | 28 | 62 | 160 | 8 | 0 | 0 | 2 | 20 | 0 | 3 | 3.92 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 76 | 33 | 33 | 20 | 11 | 3.16 | .269 | 1.09 | 7.6 | 2.2 | 7.3 | 236.1 | 200 | 95 | 83 | 30 | 58 | 191 | 5 | 0 | 0 | 0 | 23 | 3 | 2 | 3.81 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 57 | 32 | 32 | 10 | 11 | 5.50 | .329 | 1.45 | 10.3 | 2.8 | 3.9 | 206.0 | 236 | 132 | 126 | 28 | 63 | 90 | 6 | 0 | 0 | 0 | 12 | 4 | 1 | 4.87 |
| SP | Hubbell, C.Hubbell, Carl >> | 30 | 1933 | L | 42 | 32 | 32 | 10 | 16 | 4.85 | .310 | 1.33 | 9.5 | 2.5 | 4.4 | 204.0 | 215 | 113 | 110 | 25 | 56 | 99 | 1 | 0 | 0 | 0 | 15 | 4 | 6 | 4.50 |
| SP | Loaiza, E.Loaiza, Esteban >> | 32 | 2003 | R | 22 | 33 | 32 | 14 | 9 | 4.26 | .296 | 1.24 | 8.9 | 2.3 | 5.4 | 209.0 | 206 | 108 | 99 | 22 | 53 | 126 | 3 | 0 | 0 | 3 | 14 | 4 | 1 | 3.98 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 59 | 76 | 0 | 4 | 2 | 4.42 | .307 | 1.33 | 9.4 | 2.7 | 8.4 | 71.1 | 74 | 41 | 35 | 9 | 21 | 66 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 3.68 |
| RP | Caudill, B.Caudill, Bill >> | 26 | 1982 | R | 39 | 53 | 0 | 7 | 0 | 2.90 | .317 | 1.33 | 8.8 | 3.3 | 7.9 | 49.2 | 48 | 16 | 16 | 5 | 18 | 43 | 0 | 1 | 0 | 0 | 0 | 3 | 1 | 3.86 |
| SU | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 74 | 45 | 0 | 0 | 3 | 4.08 | .291 | 1.23 | 7.8 | 3.3 | 5.5 | 46.1 | 40 | 22 | 21 | 4 | 17 | 28 | 0 | 5 | 5 | 0 | 0 | 0 | 1 | 4.02 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 94 | 57 | 0 | 2 | 10 | 3.79 | .285 | 1.20 | 7.5 | 3.4 | 9.2 | 59.1 | 49 | 26 | 25 | 5 | 22 | 60 | 0 | 35 | 5 | 0 | 0 | 0 | 0 | 3.19 |
| SP | Pettitte, A.Pettitte, Andy >> | 25 | 1997 | L | 5 | 18 | 0 | 3 | 2 | 4.52 | .296 | 1.26 | 8.9 | 2.6 | 5.9 | 69.2 | 68 | 38 | 35 | 6 | 20 | 45 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 3.70 |